Evidence map›Paper›PMID 26435739›Full record

ArticleJournal of biological engineering2015

Standards not that standard.

Cristina Vilanova, Kristie Tanner, Pedro Dorado-Morales, Paula Villaescusa, Divya Chugani, Alba Frías, Ernesto Segredo, Xavier Molero, Marco Fritschi, Lucas Morales and 4 more

Abstract read
In one paragraph

Article in Journal of biological engineering, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Cristina Vilanova *Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, C. Catedràtic José Beltrán 2, 46980 Paterna, Spain.
Kristie Tanner *Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, C. Catedràtic José Beltrán 2, 46980 Paterna, Spain.
Pedro Dorado-MoralesInstitut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, C. Catedràtic José Beltrán 2, 46980 Paterna, Spain.
Paula VillaescusaInstitut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, C. Catedràtic José Beltrán 2, 46980 Paterna, Spain.
Divya ChuganiInstitut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, C. Catedràtic José Beltrán 2, 46980 Paterna, Spain.
Alba FríasInstitut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, C. Catedràtic José Beltrán 2, 46980 Paterna, Spain.
Ernesto SegredoInstitut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, C. Catedràtic José Beltrán 2, 46980 Paterna, Spain.
Xavier MoleroInstitut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, C. Catedràtic José Beltrán 2, 46980 Paterna, Spain.
Marco FritschiInstitut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, C. Catedràtic José Beltrán 2, 46980 Paterna, Spain.
Lucas MoralesInstitut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, C. Catedràtic José Beltrán 2, 46980 Paterna, Spain.
Daniel RamónBiopolis S.L, Parc Cientific Universitat de València, Paterna, Valencia Spain.
Carlos PeñaInstituto de Física Corpuscular (IFIC), CSIC - Universitat de València, Burjassot, 46100 Spain.
Juli PeretóInstitut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, C. Catedràtic José Beltrán 2, 46980 Paterna, Spain.
Manuel PorcarInstitut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, C. Catedràtic José Beltrán 2, 46980 Paterna, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a general assent on the key role of standards in Synthetic Biology. In two consecutive letters to this journal, suggestions on the assembly methods for the Registry of standard biological parts have been described. We fully agree with those authors on the need of a more flexible building strategy and we highlight in the present work two major functional challenges standardization efforts have to deal with: the need of both universal and orthogonal behaviors. We provide experimental data that clearly indicate that such engineering requirements should not be taken for granted in Synthetic Biology.

Indexed as

Biobrick partsOrthogonalityStandardizationSynthetic biology

Identifiers

PMID26435739
PMCPMC4591577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.