Evidence map›Paper›PMID 26435543›Full record

ArticleJournal of veterinary science2016

Development and evaluation of a competitive enzyme-linked immunosorbent assay using a monoclonal antibody for diagnosis of severe fever with thrombocytopenia syndrome virus in bovine sera.

Hyojin Lee, Eun-Ju Kim, Jae-Young Song, Jeong Soo Choi, Ji Youn Lee, In-Soo Cho, Yeun-Kyung Shin

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

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  14. Development of monoclonal antibody based IgG and IgM ELISA for diagnosis of severe fever with thrombocytopenia syndrome virus infection.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hyojin LeeDivision of Viral Disease, Animal and Plant Quarantine Agency, Anyang 14086, Korea.
Eun-Ju KimDivision of Viral Disease, Animal and Plant Quarantine Agency, Anyang 14086, Korea.
Jae-Young SongDivision of Viral Disease, Animal and Plant Quarantine Agency, Anyang 14086, Korea.
Jeong Soo ChoiDivision of Foreign Animal Disease, Animal and Plant Quarantine Agency, Anyang 14086, Korea.
Ji Youn LeeDivision of Foreign Animal Disease, Animal and Plant Quarantine Agency, Anyang 14086, Korea.
In-Soo ChoDivision of Foreign Animal Disease, Animal and Plant Quarantine Agency, Anyang 14086, Korea.
Yeun-Kyung ShinDivision of Viral Disease, Animal and Plant Quarantine Agency, Anyang 14086, Korea.
Animal and Plant Quarantine Agency · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe fever with thrombocytopenia syndrome (SFTS) caused by the SFTS virus (SFTSV), a phlebovirus in the family Bunyaviridae, is an emerging tick-borne infectious disease that impacts humans. This disease manifests as a decreased blood cell count and multi-organ failure, with a case-fatality rate of more than 12% in China. Because vaccines or antiviral drugs for the treatment of this disease are not available, monitoring the SFTS circulation in animals and controlling the tick-mammal cycle are important for preventing SFTS. Monoclonal antibodies against the recombinant nucleoprotein of SFTSV were generated to develop a competitive enzyme-linked immunosorbent assay (cELISA) for the detection of antibodies against SFTSV infection in cattle. The specificity and sensitivity of cELISA was assessed by comparing the results of this assay to those of an immunofluorescence assay (IFA). The results of the cELISA using 416 field bovine serum samples and laboratory-immunized positive sera showed 98.1% consistency with those of the IFA. The cELISA used in this study did not show cross-reactivity with antisera against other viral cattle diseases. The cELISA presented in this study can be applied to detect antibodies against SFTSV in cattle.

Indexed as

AnimalsAntibodies, MonoclonalAntibodies, ViralBunyaviridae InfectionsCattleCattle DiseasesEnzyme-Linked Immunosorbent AssayFluorescent Antibody TechniquePhlebovirusAntibodies, MonoclonalAntibodies, Viralcattleenzyme-linked immunosorbent assayimmunofluorescence assaysevere fever with thrombocytopenia syndrome

Identifiers

PMID26435543
PMCPMC5037297
OpenAlexW2507669933

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.