Evidence map›Paper›PMID 26433814›Full record

ArticleThe Lancet. Oncology2015

Adjuvant sorafenib for liver cancer: wrong stage, wrong dose.

Robin Kate Kelley

Abstract readComment
In one paragraph

Article in The Lancet. Oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Targeted therapy for hepatocellular carcinoma.Signal transduction and targeted therapy · 2020
    Review
  13. Emerging agents and regimens for hepatocellular carcinoma.Journal of hematology & oncology · 2019
    Review
  14. Genomic and transcriptional heterogeneity of multifocal hepatocellular carcinoma.Annals of oncology : official journal of the European Society for Medical Oncology · 2019
    Article
  15. Review
  16. Hedgehog signaling pathway affects the sensitivity of hepatoma cells to drug therapy through the ABCC1 transporter.Laboratory investigation; a journal of technical methods and pathology · 2017
    Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Robin Kate KelleyUniversity of California San Francisco, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143, USA. Electronic address: katie.kelley@ucsf.edu.
UCSF Helen Diller Family Comprehensive Cancer Center · US

Funding

Translational InformaticsP30CA082103 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jennifer Leigh Clarke · 1999 to 2026
$209.7M
UCSF Liver Core CenterP30DK026743 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Holger Willenbring · 1986 to 2026
$30.7M
NCI NIH HHS P30 CA082103NCI NIH HHS P30CA082103NIDDK NIH HHS P30 DK026743
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Catheter AblationHepatectomyAntineoplastic AgentsCarcinoma, HepatocellularFemaleHumansLiver NeoplasmsMaleNiacinamidePhenylurea CompoundsProtein Kinase InhibitorsAntineoplastic AgentsNiacinamidePhenylurea CompoundsProtein Kinase Inhibitors

Identifiers

PMID26433814
PMCPMC4811670
OpenAlexW2154928880

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.