Evidence map›Paper›PMID 26433469›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2015

International Federation of Gynecology and Obstetrics opinion on reproductive health impacts of exposure to toxic environmental chemicals.

Gian Carlo Di Renzo, Jeanne A Conry, Jennifer Blake, Mark S DeFrancesco, Nathaniel DeNicola, James N Martin, Kelly A McCue, David Richmond, Abid Shah, Patrice Sutton and 3 more

Open access · hybridAbstract read
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 142 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
142citing papers in PubMed, 3 pooled it
105.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

142 citing papers in PubMed, 3 syntheses or guidelines pooled it, 314 citations in OpenAlex.

  1. Pooled it
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  13. FIGO committee opinion: Environmental drivers of obstetric health and early childhood development.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
  14. FIGO committee opinion: Environmental drivers of gynecologic and reproductive health.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
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82 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 4 countries.

Gian Carlo Di RenzoInternational Federation of Gynecology and Obstetrics, London, UK.
Jeanne A ConryAmerican College of Obstetricians and Gynecologists, Washington, DC, USA.
Jennifer BlakeSociety of Obstetricians and Gynaecologists of Canada, Ottawa, ON, Canada.
Mark S DeFrancescoAmerican College of Obstetricians and Gynecologists, Washington, DC, USA.
Nathaniel DeNicolaAmerican College of Obstetricians and Gynecologists, Washington, DC, USA.
James N MartinAmerican College of Obstetricians and Gynecologists, Washington, DC, USA.
Kelly A McCueAmerican College of Obstetricians and Gynecologists, Washington, DC, USA.
David RichmondRoyal College of Obstetricians and Gynaecologists, London, UK.
Abid ShahRoyal College of Obstetricians and Gynaecologists, London, UK.
Patrice SuttonProgram on Reproductive Health and the Environment, University of California, San Francisco, San Francisco, CA, USA.
Tracey J WoodruffProgram on Reproductive Health and the Environment, University of California, San Francisco, San Francisco, CA, USA. Electronic address: tracey.woodruff@ucsf.edu.
Sheryl Ziemin van der PoelWorld Health Organization, Geneva, Switzerland.
Linda C GiudiceAmerican Society for Reproductive Medicine, Birmingham, AL, USA.
American Congress of Obstetricians and Gynecologists · USRoyal College of Obstetricians and Gynaecologists · GBUniversity of California, San Francisco · USAmerican Society for Reproductive Medicine · USInternational Federation of Gynaecology and Obstetrics · GBThe Society of Obstetricians and Gynaecologists of Canada · CAWorld Health Organization · CH

Funding

The UCSF Pregnancy Exposures to Environmental Chemicals (PEEC) Children's CenterP01ES022841 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOODRUFF, TRACEY J. · 2013 to 2018
$3.9M
Summit on Shaping Our Planetary LegacyR13ES026021 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOODRUFF, TRACEY J. · 2015 to 2015
$8k
NIEHS NIH HHS P01 ES022841NIEHS NIH HHS R13 ES026021PHS HHS 1R13ESO26021-01PHS HHS ESO22841World Health Organization 001
6 · The paper itself

Abstract

Exposure to toxic environmental chemicals during pregnancy and breastfeeding is ubiquitous and is a threat to healthy human reproduction. There are tens of thousands of chemicals in global commerce, and even small exposures to toxic chemicals during pregnancy can trigger adverse health consequences. Exposure to toxic environmental chemicals and related health outcomes are inequitably distributed within and between countries; universally, the consequences of exposure are disproportionately borne by people with low incomes. Discrimination, other social factors, economic factors, and occupation impact risk of exposure and harm. Documented links between prenatal exposure to environmental chemicals and adverse health outcomes span the life course and include impacts on fertility and pregnancy, neurodevelopment, and cancer. The global health and economic burden related to toxic environmental chemicals is in excess of millions of deaths and billions of dollars every year. On the basis of accumulating robust evidence of exposures and adverse health impacts related to toxic environmental chemicals, the International Federation of Gynecology and Obstetrics (FIGO) joins other leading reproductive health professional societies in calling for timely action to prevent harm. FIGO recommends that reproductive and other health professionals advocate for policies to prevent exposure to toxic environmental chemicals, work to ensure a healthy food system for all, make environmental health part of health care, and champion environmental justice.

Indexed as

Breast FeedingCost of IllnessEnvironmental ExposureEnvironmental MonitoringEnvironmental PollutantsFemaleGlobal HealthHumansInternational AgenciesPregnancyPrenatal Exposure Delayed EffectsReproductionRisk FactorsSocioeconomic FactorsEnvironmental PollutantsDevelopmental healthEnvironmental chemicalsReproductive environmental healthToxic chemicalsWomen's health

Identifiers

PMID26433469
PMCPMC6663094
OpenAlexW2179658697

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.