ArticleBMC psychiatry2015
The Danish High Risk and Resilience Study--VIA 7--a cohort study of 520 7-year-old children born of parents diagnosed with either schizophrenia, bipolar disorder or neither of these two mental disorders.
Article in BMC psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
48 citing papers in PubMed, 103 citations in OpenAlex.
- Developmental trajectories of social responsiveness and theory of mind in adolescent offspring at familial high-risk of schizophrenia or bipolar disorder and population-based controls-The Danish High Risk and Resilience Study, VIA 15.The British journal of clinical psychology · 2026Article
- Clinical Significance of Psychotic Experiences in Preadolescent Children with Non-Psychotic Mental Disorders-The Danish High Risk and Resilience Study, VIA 11.Schizophrenia bulletin · 2026Article
- Article
- Cognitive reserve in seven-year-old children at familial high risk of schizophrenia or bipolar disorder.European child & adolescent psychiatry · 2026Article
- Development of Physical Activity from Childhood to Adolescence in Offspring at Familial High Risk of Schizophrenia or Bipolar Disorder and Population-Based Controls: The Danish High Risk and Resilience Study.Schizophrenia bulletin open · 2026Article
- Study protocol for the Danish High Risk and Resilience Study VIA 19 - from age 15 to age 19: transition from adolescence to early adulthood.Frontiers in psychiatry · 2026Article
- 'Will They Have It Too?' Mothers' Perspectives of Familial Risk for Eating Disorders.Child psychiatry and human development · 2025Article
- Protective and risk factors for eating disorders: protocol for a prospective cohort study of children at familial high risk (BLOOM).BMJ open · 2025Article
- Language, Motor Ability and Related Deficits in Children at Familial Risk of Schizophrenia or Bipolar Disorder.Schizophrenia bulletin · 2025Article
- Validation of sleep-wake estimation from thigh-worn accelerometers against polysomnography in adolescents with and without mental disorders.BMC psychiatry · 2025Article
- Neurobiology and Cognition in Girls at High-Risk of Eating Disorders: Exploring Imaging-Derived Trait Markers.European eating disorders review : the journal of the Eating Disorders Association · 2025Article
- Article
- Social perception in parents with schizophrenia or bipolar disorder and their adolescent offspring - The Danish High Risk and Resilience Study.Schizophrenia research. Cognition · 2025Review
- Environmental and Genetic Influences on Developmental Outcomes Across the Domains of Language, Cognition, Motor Function, and Social Behavior.The European journal of neuroscience · 2025Article
- Maternal interleukin 6 in pregnancy is associated withPsychological medicine · 2025Article
- Family functioning in families with 11-year-old children at familial high risk of schizophrenia or bipolar disorder and population-based controls: The Danish High Risk and Resilience Study VIA 11.Psychological medicine · 2025Article
- Executive Control and Associated Brain Activity in Children With Familial High-Risk of Schizophrenia or Bipolar Disorder: A Danish Register-based Study.Schizophrenia bulletin · 2024Article
- Epigenetic and Coping Mechanisms of Stress in Affective Disorders: A Scoping Review.Medicina (Kaunas, Lithuania) · 2024Article
- The development in rating-based executive functions in children at familial high risk of schizophrenia or bipolar disorder from age 7 to age 11: the Danish high risk and resilience study.European child & adolescent psychiatry · 2024Article
- Children at Familial High risk of Schizophrenia and Bipolar Disorder Exhibit Altered Connectivity Patterns During Pre-attentive Processing of an Auditory Prediction Error.Schizophrenia bulletin · 2024Article
Corrections and comments
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Authors and funding
15 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere mental illnesses like schizophrenia and bipolar disorder are known to be diseases that to some extent, but not entirely can be understood genetically. The dominating hypothesis is that these disorders should be understood in a neurodevelopmental perspective where genes and environment as well as gene-environment-interactions contribute to the risk of developing the disease. We aim to analyse the influences of genetic risk and environmental factors in a population of 520 7-year-old children with either 0, 1 or 2 parents diagnosed with schizophrenia spectrum psychosis or bipolar disorder on mental health and level of functioning. We hypothesize that a larger proportion of children growing up with an ill parent will display abnormal or delayed development, behavioural problems or psychiatric symptoms compared to the healthy controls. METHODS/
designWe are establishing a cohort of 5207 year old children and both their parents for a comprehensive investigation with main outcome measures being neurocognition, behaviour, psychopathology and neuromotor development of the child. Parents and children are examined with a comprehensive battery of instruments and are asked for genetic material (saliva or blood) for genetic analyses. The participants are recruited via Danish registers to ensure representativity. Data from registers concerning social status, birth complications, somatic illnesses and hospitalization are included in the database. Psychological and relational factors like emotional climate in the family, degree of stimulation and support in the home and attachment style are also investigated. DISCUSSION: Data collection started January 1, 2013, and is successfully ongoing. By Aug 2015 424 families are included. About 20% of the invited families decline to participate, equal for all groups.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.