ArticleThyroid : official journal of the American Thyroid Association2015
Risk Factors for Decreased Quality of Life in Thyroid Cancer Survivors: Initial Findings from the North American Thyroid Cancer Survivorship Study.
Article in Thyroid : official journal of the American Thyroid Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 2 of them syntheses that pooled it.
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Who cites it
60 citing papers in PubMed, 2 syntheses or guidelines pooled it, 160 citations in OpenAlex.
- Thyroid disease-specific quality of life questionnaires - A systematic review.Endocrinology, diabetes & metabolism · 2022Pooled it
- Patient-Reported Quality-of-Life Outcome Measures in the Thyroid Cancer Population.Thyroid : official journal of the American Thyroid Association · 2020Pooled it
- Machine learning-based random forest for predicting decreased quality of life in thyroid cancer patients after thyroidectomy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Trial
- Longitudinal Assessment of Quality of Life Following Molecular Testing for Indeterminate Thyroid Nodules.Annals of surgical oncology · 2021Trial
- The incidence and perinatal outcomes of pregnancy-associated thyroid cancer: an Australian population-based study.Journal of the Endocrine Society · 2026Article
- The impact of coping styles on anxiety and depression trajectories in thyroid cancer surgery patients: a longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Overdiagnosis of Papillary Thyroid Cancer.JAMA network open · 2026Article
- Longitudinal relationships of malnutrition risk, sleep disturbance, and fear of cancer recurrence in thyroid cancer patients: a cross-lagged panel model.Frontiers in nutrition · 2026Article
- Allostatic load in thyroid cancer is higher than that of other cancers: A secondary analysis using NHANES.PloS one · 2026Article
- Psychological analysis of depression, anxiety, and quality of life in postoperative thyroid cancer patients: a narrative review.Thyroid research · 2025Review
- Assessing quality of life in papillary thyroid cancer through a cross-sectional comparative study of SF-26 versus ThyPRO questionnaire.Scientific reports · 2025Article
- Factors affecting the well-being of patients with thyroid cancer: results of a UK qualitative study.BMJ open · 2025Article
- A Narrative Review of the Odyssey of Thyroid Cancer Diagnosis: Can 99mTc-SESTAMIBI Molecular Imaging Replace Fine Needle Aspiration Biopsy?Medicina (Kaunas, Lithuania) · 2025Review
- Factors linked to poor self-rated health in thyroid disorder patients: findings from LASI Wave-I.Thyroid research · 2025Article
- Impact of nodal status evaluation on therapeutic strategy for clinically unifocal T1b/small T2 node negative papillary thyroid carcinoma.Endocrine · 2025Article
- Development and validation of a nomogram for predicting suicide risk factors in thyroid cancer patients following diagnosis: a population-based retrospective study.Frontiers in endocrinology · 2025Article
- Anxiety disorders in patients with thyroid nodules vs. thyroid cancer: a retrospective cohort study.Frontiers in endocrinology · 2025Article
- The Unappreciated Value of a Cheap, 'Good Enough' Method of Detecting Thyroid Cancer.Journal of clinical medicine · 2024Review
- Psychological impacts of lobectomy and total thyroidectomy in PTC measuring 1 to 4 cm with low to intermediate risk of recurrence.Endocrine · 2024Article
- Depression, Anxiety, and Pain Predict Quality of Life in Patients with Differentiated Thyroid Cancer Postradiotherapy Ablation in Taiwan: A 48-Week Follow-Up Study.Current oncology (Toronto, Ont.) · 2024Article
Corrections and comments
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Authors and funding
16 authors at 9 institutions in 2 countries.
Funding
Abstract
backgroundThe prevalence of thyroid cancer survivors is rising rapidly due to the combination of an increasing incidence, high survival rates, and a young age at diagnosis. The physical and psychosocial morbidity of thyroid cancer has not been adequately described, and this study therefore sought to improve the understanding of the impact of thyroid cancer on quality of life (QoL) by conducting a large-scale survivorship study.
methodsThyroid cancer survivors were recruited from a multicenter collaborative network of clinics, national survivorship groups, and social media. Study participants completed a validated QoL assessment tool that measures four morbidity domains: physical, psychological, social, and spiritual effects. Data were also collected on participant demographics, medical comorbidities, tumor characteristics, and treatment modalities.
resultsA total of 1174 participants with thyroid cancer were recruited. Of these, 89.9% were female, with an average age of 48 years, and a mean time from diagnosis of five years. The mean overall QoL was 5.56/10, with 0 being the worst. Scores for each of the sub-domains were 5.83 for physical, 5.03 for psychological, 6.48 for social, and 5.16 for spiritual well-being. QoL scores begin to improve five years after diagnosis. Female sex, young age at diagnosis, and lower educational attainment were highly predictive of decreased QoL.
conclusionThyroid cancer diagnosis and treatment can result in a decreased QoL. The present findings indicate that better tools to measure and improve thyroid cancer survivor QoL are needed. The authors plan to follow-up on these findings in the near future, as enrollment and data collection are ongoing.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.