SynthesisJournal of neurotrauma2021
Adherence to Guidelines in Adult Patients with Traumatic Brain Injury: A Living Systematic Review.
Synthesis in Journal of neurotrauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 48 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
International Prospective Observational StudY on iNtrAcranial PreSsurE in Intensive Care (ICU) (SynapseICU)
Evaluation of Intracranial Pressure Time Dose by the New Integra CereLink ICP Monitor
Who cites it
48 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Past, present and future of living systematic review: a bibliometrics analysis.BMJ global health · 2022Pooled it
- Blood-Based Protein Biomarkers for the Management of Traumatic Brain Injuries in Adults Presenting to Emergency Departments with Mild Brain Injury: A Living Systematic Review and Meta-Analysis.Journal of neurotrauma · 2021Pooled it
- Cultural bias in large language models' ability to follow neuroradiology guidelines.European radiology · 2026Article
- Adherence to strong recommendations of the German Polytrauma Guideline: an analysis of TraumaRegister DGU data over a decade.Scientific reports · 2026Article
- Can Neurocritical Care Guidelines Developed in High-Income Countries be Relevant to Low- and Middle-Income Countries?Neurocritical care · 2025Article
- Traumatic Brain Injury: Advances in Diagnostic Techniques and Treatment Modalities.Journal of clinical medicine · 2025Review
- Association of early in-hospital endotracheal intubation with clinical outcomes in patients with traumatic coma: a multicenter observational study.Critical care (London, England) · 2025Observational
- A head-to-head comparison of S100B and GFAP/UCH-L1 for detection of traumatic intracranial lesions in a Scandinavian trauma cohort.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025Article
- Practitioner's perception of myasthenia gravis management recommendations in clinical practice: a cross-sectional survey study.Therapeutic advances in chronic disease · 2025Article
- Traumatic brain injury (TBI) triage tool for low-risk patients: standardizing TBI care at a Level 1 trauma center.Trauma surgery & acute care open · 2025Article
- Improving Patient Outcomes in mTBI: The Role of Integrated Nursing Interventions in the Emergency Department.Therapeutics and clinical risk management · 2025Article
- Measuring evidence-based clinical guideline compliance in the paediatric intensive care unit.BMJ open quality · 2024Article
- The death of a neurotrauma trial lessons learned from the prematurely halted randomized evaluation of surgery in elderly with traumatic acute subdural hematoma (RESET-ASDH) trial.Brain & spine · 2024Article
- The Blunt Liver and Spleen Trauma (BLAST) audit: national survey and prospective audit of children with blunt liver and spleen trauma in major trauma centres.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Article
- Intramural Healthcare Consumption and Costs After Traumatic Brain Injury: A Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Study.Journal of neurotrauma · 2023Observational
- Early Signs of Elevated Intracranial Pressure on Computed Tomography Correlate With Measured Intracranial Pressure in the Intensive Care Unit and Six-Month Outcome After Moderate to Severe Traumatic Brain Injury.Journal of neurotrauma · 2023Article
- Relationship between guideline adherence and outcomes in severe traumatic brain injury.Annals of the Royal College of Surgeons of England · 2023Review
- Analysis of the primary utilization of videolaryngoscopy in prehospital emergency care in Germany.Die Anaesthesiologie · 2023Article
- Diagnostic performance of biomarker S100B and guideline adherence in routine care of mild head trauma.Scandinavian journal of trauma, resuscitation and emergency medicine · 2023Article
- What are the perceptions of intensive care staff about their sedation practices when caring for a mechanically ventilated patient?: A systematic mixed-methods review.International journal of nursing studies advances · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Guidelines aim to improve the quality of medical care and reduce treatment variation. The extent to which guidelines are adhered to in the field of traumatic brain injury (TBI) is unknown. The objectives of this systematic review were to (1) quantify adherence to guidelines in adult patients with TBI, (2) examine factors influencing adherence, and (3) study associations of adherence to clinical guidelines and outcome. We searched EMBASE, MEDLINE, Cochrane Central, PubMed, Web of Science, PsycINFO, SCOPUS, CINAHL, and grey literature in October 2014. We included studies of evidence-based (inter)national guidelines that examined the acute treatment of adult patients with TBI. Methodological quality was assessed using the Research Triangle Institute item bank and Quality in Prognostic Studies Risk of Bias Assessment Instrument. Twenty-two retrospective and prospective observational cohort studies, reported in 25 publications, were included, describing adherence to 13 guideline recommendations. Guideline adherence varied considerably between studies (range 18-100%) and was higher in guideline recommendations based on strong evidence compared with those based on lower evidence, and lower in recommendations of relatively more invasive procedures such as craniotomy. A number of patient-related factors, including age, Glasgow Coma Scale, and intracranial pathology, were associated with greater guideline adherence. Guideline adherence to Brain Trauma Foundation guidelines seemed to be associated with lower mortality. Guideline adherence in TBI is suboptimal, and wide variation exists between studies. Guideline adherence may be improved through the development of strong evidence for guidelines. Further research specifying hospital and management characteristics that explain variation in guideline adherence is warranted.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.