Evidence map›Paper›PMID 26431488›Full record

ArticlePloS one2015

Metagenomic Human Repiratory Air in a Hospital Environment.

Yi Yu Lai, Yanming Li, Jidong Lang, Xunliang Tong, Lina Zhang, Jianhuo Fang, Jingli Xing, Meng Cai, Hongtao Xu, Yan Deng and 2 more

RetractedAbstract readRetracted Publication
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Yi Yu LaiGenomics and Synthetic Biology Center, Tsinghua University, Beijing, China.
Yanming LiDepartment of Respiratory and Critical Care Medicine, Beijing Hospital, Beijing, China.
Jidong LangGenomics and Synthetic Biology Center, Tsinghua University, Beijing, China; School of Medicine, Tsinghua University, Beijing, China.
Xunliang TongDepartment of Respiratory and Critical Care Medicine, Beijing Hospital, Beijing, China.
Lina ZhangGenomics and Synthetic Biology Center, Tsinghua University, Beijing, China.
Jianhuo FangGenomics and Synthetic Biology Center, Tsinghua University, Beijing, China.
Jingli XingGenomics and Synthetic Biology Center, Tsinghua University, Beijing, China.
Meng CaiDepartment of Hospital Infection Control, Beijing Hospital, Beijing, China.
Hongtao XuDepartment of Medicine Laboratory, Beijing Hospital, Beijing, China.
Yan DengState key laboratory of precision measurement technology and instruments, Tsinghua university, Beijing, China.
Fei XiaoBeijing Hospital, Beijing Institute of Geriatrics, Key Laboratory of Geriatrics, Ministry of Health, Beijing, China.
Geng TianGenomics and Synthetic Biology Center, Tsinghua University, Beijing, China; School of Medicine, Tsinghua University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hospital-acquired infection (HAI) or nosocomial infection is an issue that frequent hospital environment. We believe conventional regulated Petri dish method is insufficient to evaluate HAI. To address this problem, metagenomic sequencing was applied to screen airborne microbes in four rooms of Beijing Hospital. With air-in amount of sampler being setup to one person's respiration quantity, metagenomic sequencing identified huge numbers of species in the rooms which had already qualified widely accepted petridish exposing standard, imposing urgency for new technology. Meanwhile,the comparative culture only got small portion of recovered species and remain blind for even cultivable pathogens reminded us the limitations of old technologies. To the best of our knowledge, the method demonstrated in this study could be broadly applied in hospital indoor environment for various monitoring activities as well as HAI study. It is also potential as a transmissible pathogen real-time modelling system worldwide.

Identifiers

PMID26431488
PMCPMC4592066

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.