Evidence map›Paper›PMID 26431463›Full record

ArticleAutophagy2015

ncRDeathDB: A comprehensive bioinformatics resource for deciphering network organization of the ncRNA-mediated cell death system.

Deng Wu, Yan Huang, Juanjuan Kang, Kongning Li, Xiaoman Bi, Ting Zhang, Nana Jin, Yongfei Hu, Puwen Tan, Lu Zhang and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.

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  7. Autophagy3D: a comprehensive autophagy structure database.Database : the journal of biological databases and curation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Deng Wua College of Bioinformatics Science and Technology; Harbin Medical University ; Harbin , China.
Yan Huanga College of Bioinformatics Science and Technology; Harbin Medical University ; Harbin , China.
Juanjuan Kanga College of Bioinformatics Science and Technology; Harbin Medical University ; Harbin , China.
Kongning Lia College of Bioinformatics Science and Technology; Harbin Medical University ; Harbin , China.
Xiaoman Bia College of Bioinformatics Science and Technology; Harbin Medical University ; Harbin , China.
Ting Zhanga College of Bioinformatics Science and Technology; Harbin Medical University ; Harbin , China.
Nana Jina College of Bioinformatics Science and Technology; Harbin Medical University ; Harbin , China.
Yongfei Hua College of Bioinformatics Science and Technology; Harbin Medical University ; Harbin , China.
Puwen Tana College of Bioinformatics Science and Technology; Harbin Medical University ; Harbin , China.
Lu Zhanga College of Bioinformatics Science and Technology; Harbin Medical University ; Harbin , China.
Ying Yia College of Bioinformatics Science and Technology; Harbin Medical University ; Harbin , China.
Wenjun Shenc Department of Biochemistry and Molecular Biology, Shantou University Medical College ; Shantou , China.
Jian Huangb Bioinformatics Center; School of Life Science; University of Electronic Science and Technology of China ; Chengdu , China.
Xiaobo Lid Department of Pathology, Harbin Medical University ; Harbin , China.
Xia Lia College of Bioinformatics Science and Technology; Harbin Medical University ; Harbin , China.
Jianzhen Xuc Department of Biochemistry and Molecular Biology, Shantou University Medical College ; Shantou , China.
Dong Wanga College of Bioinformatics Science and Technology; Harbin Medical University ; Harbin , China.
Harbin Medical University · CNShantou University Medical College · CNInstitute of Bioinformatics · INShantou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Programmed cell death (PCD) is a critical biological process involved in many important processes, and defects in PCD have been linked with numerous human diseases. In recent years, the protein architecture in different PCD subroutines has been explored, but our understanding of the global network organization of the noncoding RNA (ncRNA)-mediated cell death system is limited and ambiguous. Hence, we developed the comprehensive bioinformatics resource (ncRDeathDB, www.rna-society.org/ncrdeathdb ) to archive ncRNA-associated cell death interactions. The current version of ncRDeathDB documents a total of more than 4600 ncRNA-mediated PCD entries in 12 species. ncRDeathDB provides a user-friendly interface to query, browse and manipulate these ncRNA-associated cell death interactions. Furthermore, this resource will help to visualize and navigate current knowledge of the noncoding RNA component of cell death and autophagy, to uncover the generic organizing principles of ncRNA-associated cell death systems, and to generate valuable biological hypotheses.

Indexed as

Computational BiologyDatabases, GeneticApoptosisAutophagyHumansProteinsRNA, UntranslatedSignal TransductionProteinsRNA, Untranslatedautophagycell deathcrosstalkdatabasencRNAnetwork

Identifiers

PMID26431463
PMCPMC4824571
OpenAlexW1857680029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.