ArticlePloS one2015
Reversing Stimulus Timing in Visual Conditioning Leads to Memories with Opposite Valence in Drosophila.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- Article
- Diversity of visual inputs to Kenyon cells of the Drosophila mushroom body.Nature communications · 2024Article
- A New Behavioral Paradigm for Visual Classical Conditioning inBio-protocol · 2023Article
- Diversity of visual inputs to Kenyon cells of thebioRxiv : the preprint server for biology · 2023Article
- Local 5-HT signaling bi-directionally regulates the coincidence time window for associative learning.Neuron · 2023Article
- Aversive Bimodal Associations Differently Impact Visual and Olfactory Memory Performance iniScience · 2022Article
- Idiosyncratic learning performance in flies.Biology letters · 2022Article
- Drosophila Passive Avoidance Behavior as a New Paradigm to Study Associative Aversive Learning.Journal of visualized experiments : JoVE · 2021Article
- Article
- Reinforcement signaling of punishment versus relief in fruit flies.Learning & memory (Cold Spring Harbor, N.Y.) · 2018Article
- Functional architecture of reward learning in mushroom body extrinsic neurons of larval Drosophila.Nature communications · 2018Article
- How Swift Is Cry-Mediated Magnetoreception? Conditioning in an American Cockroach Shows Sub-second Response.Frontiers in behavioral neuroscience · 2018Article
- Aversive olfactory associative memory loses odor specificity over time.The Journal of experimental biology · 2017Article
- Aversive Learning of Colored Lights in Walking Honeybees.Frontiers in behavioral neuroscience · 2017Article
- Requirement of NF-kappa B Activation in Different Mice Brain Areas during Long-Term Memory Consolidation in Two Contextual One-Trial Tasks with Opposing Valences.Frontiers in molecular neuroscience · 2017Article
- Independent natural genetic variation of punishment- versus relief-memory.Biology letters · 2016Article
- Gustatory processing and taste memory in Drosophila.Journal of neurogenetics · 2016Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animals need to associate different environmental stimuli with each other regardless of whether they temporally overlap or not. Drosophila melanogaster displays olfactory trace conditioning, where an odor is followed by electric shock reinforcement after a temporal gap, leading to conditioned odor avoidance. Reversing the stimulus timing in olfactory conditioning results in the reversal of memory valence such that an odor that follows shock is later on approached (i.e. relief conditioning). Here, we explored the effects of stimulus timing on memory in another sensory modality, using a visual conditioning paradigm. We found that flies form visual memories of opposite valence depending on stimulus timing and can associate a visual stimulus with reinforcement despite being presented with a temporal gap. These results suggest that associative memories with non-overlapping stimuli and the effect of stimulus timing on memory valence are shared across sensory modalities.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.