Evidence map›Paper›PMID 26430819›Full record

Trial reportCyberpsychology, behavior and social networking2016

Virtual Reality-Enhanced Cognitive-Behavioral Therapy for Morbid Obesity: A Randomized Controlled Study with 1 Year Follow-Up.

Gian Mauro Manzoni, Gian Luca Cesa, Monica Bacchetta, Gianluca Castelnuovo, Sara Conti, Andrea Gaggioli, Fabrizia Mantovani, Enrico Molinari, Georgina Cárdenas-López, Giuseppe Riva

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Cyberpsychology, behavior and social networking, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05273515 (The Acceptability and Feasibility of 3D Reconstruction and Virtual Reality in Addressing Body Image in Bariatric Surgery), which is not on this map. Cited by 49 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 10 pooled it
7.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05273515 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Acceptability and Feasibility of 3D Reconstruction and Virtual Reality in Addressing Body Image in Bariatric Surgery

TypeinterventionalSponsorImperial College LondonRan2022 to 2022Enrolled10ConditionsObesity, Body Image Disorder, Bariatric Surgery CandidateArmsVirtual Reality and 3D Reconstruction
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 10 syntheses or guidelines pooled it, 116 citations in OpenAlex.

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  9. Neuroscience of Virtual Reality: From Virtual Exposure to Embodied Medicine.Cyberpsychology, behavior and social networking · 2019
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  15. Exploring Virtual Reality for Body Image Assessment and Psychological Interventions in Individuals With Obesity: a Comprehensive Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Gian Mauro Manzoni1 Psychology Research Laboratory, Ospedale San Giuseppe, Istituto Auxologico Italiano , Verbania, Italy .
Gian Luca Cesa3 Applied Technology for Neuro Psychology Lab, Istituto Auxologico Italiano , Verbania, Italy .
Monica Bacchetta3 Applied Technology for Neuro Psychology Lab, Istituto Auxologico Italiano , Verbania, Italy .
Gianluca Castelnuovo1 Psychology Research Laboratory, Ospedale San Giuseppe, Istituto Auxologico Italiano , Verbania, Italy .
Sara Conti3 Applied Technology for Neuro Psychology Lab, Istituto Auxologico Italiano , Verbania, Italy .
Andrea Gaggioli2 Department of Psychology, Catholic University of the Sacred Heart , Milan, Italy .
Fabrizia Mantovani5 CESCOM-Centre for Research in Communication Sciences, University of Milan-Bicocca , Milan, Italy .
Enrico Molinari1 Psychology Research Laboratory, Ospedale San Giuseppe, Istituto Auxologico Italiano , Verbania, Italy .
Georgina Cárdenas-López6 Laboratorio de Enseñanza Virtual y Ciberpsicología, Facultad de Psicología, Universidad Nacional Autónoma de México , México, Mexico .
Giuseppe Riva2 Department of Psychology, Catholic University of the Sacred Heart , Milan, Italy .
IRCCS Istituto Auxologico Italiano · ITUniversità Cattolica del Sacro Cuore · ITOspedale San Giuseppe · ITUniversidad Nacional Autónoma de México · MXUniversity of Milano-Bicocca · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is well known that obesity has a multifactorial etiology, including biological, environmental, and psychological causes. For this reason, obesity treatment requires a more integrated approach than the standard behavioral treatment based on dietary and physical activity only. To test the long-term efficacy of an enhanced cognitive-behavioral therapy (CBT) of obesity, including a virtual reality (VR) module aimed at both unlocking the negative memory of the body and to modify its behavioral and emotional correlates, 163 female morbidly obese inpatients (body mass index >40) were randomly assigned to three conditions: a standard behavioral inpatient program (SBP), SBP plus standard CBT, and SBP plus VR-enhanced CBT. Patients' weight, eating behavior, and body dissatisfaction were measured at the start and upon completion of the inpatient program. Weight was assessed also at 1 year follow-up. All measures improved significantly at discharge from the inpatient program, and no significant difference was found among the conditions. However, odds ratios showed that patients in the VR condition had a greater probability of maintaining or improving weight loss at 1 year follow-up than SBP patients had (48% vs. 11%, p = 0.004) and, to a lesser extent, than CBT patients had (48% vs. 29%, p = 0.08). Indeed, only the VR-enhanced CBT was effective in further improving weight loss at 1 year follow-up. On the contrary, participants who received only the inpatient program regained back, on average, most of the weight they had lost. Findings support the hypothesis that a VR module addressing the locked negative memory of the body may enhance the long-term efficacy of standard CBT.

Indexed as

AdultBody ImageBody Mass IndexCognitive Behavioral TherapyFeeding BehaviorFemaleFollow-Up StudiesHumansMemoryMiddle AgedObesity, MorbidPersonal SatisfactionTreatment OutcomeVirtual Reality Exposure TherapyWeight LossYoung Adult

Identifiers

PMID26430819
PMCPMC4770914
OpenAlexW2188386313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.