Experimental Models of Microvascular Immunopathology: The Example of Cerebral Malaria.

Fatima El-Assaad, Valery Combes, Georges Er Grau

Open access · greenAbstract read

In one paragraph

Article in Journal of neuroinfectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it

0cells of the map it votes in

4citing papers in PubMed

1.0field-weighted citation impact, top 19% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

The Ins and Outs of Cerebral Malaria Pathogenesis: Immunopathology, Extracellular Vesicles, Immunometabolism, and Trained Immunity.Frontiers in immunology · 2019
Review
Genetic analysis of cerebral malaria in the mouse model infected with Plasmodium berghei.Mammalian genome : official journal of the International Mammalian Genome Society · 2018
Review
Differentially expressed microRNAs in experimental cerebral malaria and their involvement in endocytosis, adherens junctions, FoxO and TGF-β signalling pathways.Scientific reports · 2018
Article
Acute Malaria Induces PD1+CTLA4+ Effector T Cells with Cell-Extrinsic Suppressor Function.PLoS pathogens · 2016
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Fatima El-AssaadVascular Immunology Unit, Department of Pathology, Sydney Medical School, Medical Foundation Building, The University of Sydney Level 2, Room 20892-94 Parramatta Rd, Sydney, NSW, 2006, Australia.

Valery CombesVascular Immunology Unit, Department of Pathology, Sydney Medical School, Medical Foundation Building, The University of Sydney Level 2, Room 20892-94 Parramatta Rd, Sydney, NSW, 2006, Australia.

Georges Er GrauProfessor Chair of Vascular Immunology, Department of Pathology, Sydney Medical School, The University of Sydney, Address: Medical Foundation Building (K25)Room 208, 92 - 94 Parramatta Rd, Sydney, NSW, 2006, Australia.

The University of Sydney · AU

Funding

Microparticles, a new player in cerebral malaria pathogenesisR01NS079873 · NINDS · LA JOLLA INFECTIOUS DISEASE INSTITUTE · PI COMBES, VALERY MADELEINE · 2012 to 2015

$1.3M

NINDS NIH HHS R01 NS079873

6 · The paper itself

Abstract

Human cerebral malaria is a severe and often lethal complication of

Indexed as

Cerebral malariaExperimental malariaMalariaPlasmodium Immunopathology

Identifiers

PMID26430675

PMCPMC4586166

OpenAlexW2186834513

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.