Evidence map›Paper›PMID 26430597›Full record

ArticleGlobal spine journal2015

Factors Associated with Life Expectancy in Patients with Metastatic Spine Disease from Adenocarcinoma of the Lung.

C Rory Goodwin, Mohamed H Khattab, Eric W Sankey, Benjamin D Elder, Thomas A Kosztowski, Rachel Sarabia-Estrada, Ali Bydon, Timothy F Witham, Jean-Paul Wolinsky, Ziya L Gokaslan and 1 more

Abstract read
In one paragraph

Article in Global spine journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  2. Pooled it
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  15. Survival in patients with surgically treated spinal metastases.Journal of craniovertebral junction & spine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

C Rory GoodwinDepartment of Neurosurgery, The Johns Hopkins University, Baltimore, Maryland, United States.
Mohamed H KhattabDepartment of Neurosurgery, The Johns Hopkins University, Baltimore, Maryland, United States.
Eric W SankeyDepartment of Neurosurgery, The Johns Hopkins University, Baltimore, Maryland, United States.
Benjamin D ElderDepartment of Neurosurgery, The Johns Hopkins University, Baltimore, Maryland, United States.
Thomas A KosztowskiDepartment of Neurosurgery, The Johns Hopkins University, Baltimore, Maryland, United States.
Rachel Sarabia-EstradaDepartment of Neurosurgery, The Johns Hopkins University, Baltimore, Maryland, United States.
Ali BydonDepartment of Neurosurgery, The Johns Hopkins University, Baltimore, Maryland, United States.
Timothy F WithamDepartment of Neurosurgery, The Johns Hopkins University, Baltimore, Maryland, United States.
Jean-Paul WolinskyDepartment of Neurosurgery, The Johns Hopkins University, Baltimore, Maryland, United States.
Ziya L GokaslanDepartment of Neurosurgery, The Johns Hopkins University, Baltimore, Maryland, United States.
Daniel M SciubbaDepartment of Neurosurgery, The Johns Hopkins University, Baltimore, Maryland, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Study Design Retrospective study. Objective Our objective was to identify preoperative prognostic factors associated with survival in patients with spinal metastasis from lung carcinoma. Methods A retrospective analysis of 26 patients diagnosed with lung carcinoma metastatic to the spinal column was performed to determine factors associated with survival. We used 3 months survival as the clinical cutoff for whether surgical intervention should be performed. We analyzed patients who survived less than 3 months compared with those who survived more than 3 months. Demographic, preoperative, operative, and postoperative factors including functional scores were collected for analysis. Results The median survival for all patients in our study was 3.5 months. We found a statistically significant difference between the group that survived less than 3 months and the group that survived greater than 3 months in terms of extrathoracic metastasis, visceral metastasis, and average postoperative modified Rankin score. Conclusion Determining which patients with lung cancer spinal metastases will benefit from surgical intervention is often dictated by the patient's predicted life expectancy. Factors associated with poorer prognosis include age, functional status, visceral metastases, and extrathoracic metastases. Although the prognosis for patients with lung cancer spinal metastases is poor, some patients may experience long-term benefit from surgical intervention.

Indexed as

adenocarcinomalife expectancylung cancermetastasisprognostic factorsspinesurgerytumor

Identifiers

PMID26430597
PMCPMC4577314

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.