Evidence map›Paper›PMID 26430439›Full record

ArticlePakistan journal of medical sciences

Differences in various biochemical and clinical parameters with respect to family history of Non Communicable Diseases in fourth year MBBS students of Karachi, Pakistan.

Khalid Abdul Basit, Asher Fawwad, Muhammad Asadullah Munir, Iftikhar Ahmed Siddiqui, Sidra Siddiqui, Abdul Basit

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In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Khalid Abdul BasitKhalid Abdul Basit, Student, MBBS, Dow University of Health Sciences, Karachi, Pakistan.
Asher FawwadAsher Fawwad, M.phil. Assistant Prof., Senior Research Scientist, Research Department, Baqai Medical University, Baqai Institute of Diabetology and Endocrinology, Plot No. 1-2, II-B, Nazimabad No.2, Karachi-74600, Pakistan.
Muhammad Asadullah MunirAsher Fawwad, M.phil. Assistant Prof., Senior Research Scientist, Research Department, Baqai Medical University, Baqai Institute of Diabetology and Endocrinology, Plot No. 1-2, II-B, Nazimabad No.2, Karachi-74600, Pakistan.
Iftikhar Ahmed SiddiquiIftikhar Ahmed Siddiqui, PhD. Chairman & Professor of Biochemistry, Department of Biochemistry, Baqai Medical University, Karachi, Pakistan.
Sidra SiddiquiSidra Siddiqui, M.Sc. Statistician, Research Department, Baqai Medical University, Baqai Institute of Diabetology and Endocrinology, Plot No. 1-2, II-B, Nazimabad No.2, Karachi-74600, Pakistan.
Abdul BasitAbdul Basit, F.R.C.P. Professor of Medicine, Department of Medicine, Baqai Medical University, Baqai Institute of Diabetology and Endocrinology, Plot No. 1-2, II-B, Nazimabad No.2, Karachi-74600, Pakistan.
National Student Clearinghouse Research Center · USBaqai Medical University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo observe the differences of various biochemical and clinical parameters with respect to Family History (FH) of Non-communicable Diseases (NCDs) in fourth year Bachelor of Medicine, Bachelor of Surgery (MBBS) students.

methodsThis observational study was conducted at Baqai Institute of Diabetology & Endocrinology from December 2013 to January 2014. Total 50 medical students from Dow University of Health Sciences (DUHS) participated in the study. Statistical Package for Social Sciences (SPSS) version 13 was used to analyze the data. For cross tabulation and mean comparison z-test and t test were applied.

resultsOut of 50 subjects, there were 26 (52%) females. Mean age of the study population was 21.56 ± 0.90 years. Mean serum cholesterol levels with positive FH of NCDs was significantly higher than negative FH of NCDs (p=0.005). Mean value of low density lipoprotein (LDL) of positive family history of NCDs was found higher than those with negative FH (p=0.006) being statistically significant. The insulin levels in subjects with positive FH of NCDs were higher than subjects with negative FH of NCDs (p=0.685). However, serum leptin and plasma renin showed no significant difference with the negative FH of NCDs being higher compared to positive FH of NCDs (p=0.068) and (p=0.884) respectively. However, Waist circumference, Body mass index and central obesity in subjects with positive FH of NCDs shows increasing trend but no statistically significant difference (p > 0.05) was observed.

conclusionIn our study of various biochemical and clinical parameters with respect to FH of NCDs, Serum Cholesterol and LDL levels were observed higher and statistically significant.

Indexed as

LeptinMedical StudentNon-communicable diseaseRenin

Identifiers

PMID26430439
PMCPMC4590368
OpenAlexW2419480677

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.