Evidence map›Paper›PMID 26430371›Full record

ArticleEuropean journal of dentistry

Periodontal health status in patients treated with the Invisalign(®) system and fixed orthodontic appliances: A 3 months clinical and microbiological evaluation.

Luca Levrini, Alessandro Mangano, Paola Montanari, Silvia Margherini, Alberto Caprioglio, Gian Marco Abbate

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04139538 (Changes of Oral Microbiome and Immunogenity of Saliva During Orthodontic Therapy With Aligners and Multibracket Therapy - a Pilot Study), which is not on this map. Cited by 76 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 7 pooled it
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04139538 naunknown statusnot on this map

Changes of Oral Microbiome and Immunogenity of Saliva During Orthodontic Therapy With Aligners and Multibracket Therapy - a Pilot Study

TypeinterventionalSponsorMedical University of ViennaRan2019 to 2024Enrolled40ConditionsOrthodontic Appliances, Removable, Orthodontic Appliances, Fixed, Oral Microbiome, Cell CultureArmsorthodontic treatment
3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 7 syntheses or guidelines pooled it, 139 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Digital versus Conventional Impression Taking Focusing on Interdental Areas: A Clinical Trial.International journal of environmental research and public health · 2020
    Trial
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Luca LevriniDepartment of Morphological and Surgical Sciences, University of Insubria, Varese, Italy.
Alessandro ManganoOro Cranio Facial Disease and Medicine Research Centre, University of Insubria, Varese, Italy.
Paola MontanariDepartment of Morphological and Surgical Sciences, University of Insubria, Varese, Italy.
Silvia MargheriniDepartment of Morphological and Surgical Sciences, University of Insubria, Varese, Italy.
Alberto CaprioglioDepartment of Morphological and Surgical Sciences, University of Insubria, Varese, Italy.
Gian Marco AbbateDepartment of Morphological and Surgical Sciences, University of Insubria, Varese, Italy.
University of Insubria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this prospective study was to compare the periodontal health and the microbiological changes via real-time polymerase chain reaction (PCR) in patients treated with fixed orthodontic appliances and Invisalign(®) system (Align Technology, Santa Clara, California). MATERIALS AND

methodsSeventy-seven patients were enrolled in this study and divided into three groups (Invisalign(®) group, fixed orthodontic appliances group and control group). Plaque index, probing depth, bleeding on probing were assessed. Total biofilm mass and periodontal pathogens were analyzed and detected via real-time PCR. All these data were analyzed at the T0 (beginning of the treatment) T1 (1-month) and T2 (3 months); and statistically compared using the Mann-Whitney test for independent groups.

resultsAfter 1-month and after 3 months of treatment there was only one sample with periodontopathic anaerobes found in patient treated using fixed orthodontic appliances. The Invisalign(®) group showed better results in terms of periodontal health and total biofilm mass compared to the fixed orthodontic appliance group. A statistical significant difference (P < 0.05) at the T2 in the total biofilm mass was found between the two groups.

conclusionPatients undergoing orthodontic treatment with the Invisalign(®) System show a superior periodontal health in the short-term when compared to patients in treatment with fixed orthodontic appliances. Invisalign(®) should be considered as a first treatment option in patients with risk of developing periodontal disease.

Indexed as

Clear alignersfixed orthodontic treatmentInvisalignmicrobiological evaluationperiodontal health

Identifiers

PMID26430371
PMCPMC4569994
OpenAlexW1936804495

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.