ArticleProceedings of SPIE--the International Society for Optical Engineering2015
Estimating ROI activity concentration with photon-processing and photon-counting SPECT imaging systems.
Article in Proceedings of SPIE--the International Society for Optical Engineering, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Evolving SPECT-CT technology.The British journal of radiology · 2026Review
- CTLESS: A scatter-window projection and deep learning-based transmission-less attenuation compensation method for myocardial perfusion SPECT.IEEE transactions on medical imaging · 2024Article
- A list-mode multi-energy window low-count SPECT reconstruction method for isotopes with multiple emission peaks.EJNMMI physics · 2023Article
- Article
- Development and task-based evaluation of a scatter-window projection and deep learning-based transmission-less attenuation compensation method for myocardial perfusion SPECT.Proceedings of SPIE--the International Society for Optical Engineering · 2023Article
- A Projection-Domain Low-Count Quantitative SPECT Method forIEEE transactions on radiation and plasma medical sciences · 2023Article
- Effect on null spaces of list-mode imaging systems due to increasing the size of attribute space.Journal of the Optical Society of America. A, Optics, image science, and vision · 2021Article
- Task-based assessment of binned and list-mode SPECT systems.Proceedings of SPIE--the International Society for Optical Engineering · 2021Article
- A physics and learning-based transmission-less attenuation compensation method for SPECT.Proceedings of SPIE--the International Society for Optical Engineering · 2021Article
- Fisher information analysis of list-mode SPECT emission data for joint estimation of activity and attenuation distribution.Inverse problems · 2020Article
- A LIST-MODE OSEM-BASED ATTENUATION AND SCATTER COMPENSATION METHOD FOR SPECT.Proceedings. IEEE International Symposium on Biomedical Imaging · 2020Article
- Towards continuous-to-continuous 3D imaging in the real world.Physics in medicine and biology · 2019Article
- A no-gold-standard technique for objective assessment of quantitative nuclear-medicine imaging methods.Physics in medicine and biology · 2016Article
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2 authors.
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Abstract
Recently a new class of imaging systems, referred to as photon-processing (PP) systems, are being developed that uses real-time maximum-likelihood (ML) methods to estimate multiple attributes per detected photon and store these attributes in a list format. PP systems could have a number of potential advantages compared to systems that bin photons based on attributes such as energy, projection angle, and position, referred to as photon-counting (PC) systems. For example, PP systems do not suffer from binning-related information loss and provide the potential to extract information from attributes such as energy deposited by the detected photon. To quantify the effects of this advantage on task performance, objective evaluation studies are required. We performed this study in the context of quantitative 2-dimensional single-photon emission computed tomography (SPECT) imaging with the end task of estimating the mean activity concentration within a region of interest (ROI). We first theoretically outline the effect of null space on estimating the mean activity concentration, and argue that due to this effect, PP systems could have better estimation performance compared to PC systems with noise-free data. To evaluate the performance of PP and PC systems with noisy data, we developed a singular value decomposition (SVD)-based analytic method to estimate the activity concentration from PP systems. Using simulations, we studied the accuracy and precision of this technique in estimating the activity concentration. We used this framework to objectively compare PP and PC systems on the activity concentration estimation task. We investigated the effects of varying the size of the ROI and varying the number of bins for the attribute corresponding to the angular orientation of the detector in a continuously rotating SPECT system. The results indicate that in several cases, PP systems offer improved estimation performance compared to PC systems.
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