Evidence map›Paper›PMID 26430215›Full record

ReviewCold Spring Harbor perspectives in biology2015

Vertebrate Reproduction.

Sally Kornbluth, Rafael Fissore

Open access · bronzeAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Signals and Receptors.Cold Spring Harbor perspectives in biology · 2016
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Sally KornbluthDuke University School of Medicine, Durham, North Carolina 27710.
Rafael FissoreUniversity of Massachusetts, Amherst, Veterinary and Animal Sciences, Amherst, Massachusetts 01003.
Duke University · USUniversity of Massachusetts Amherst · US

Funding

Control of caspase activation in apoptosisR01GM080333 · NIGMS · DUKE UNIVERSITY · PI KORNBLUTH, SALLY A · 2007 to 2015
$2.6M
NIGMS NIH HHS R01 GM080333
6 · The paper itself

Abstract

Vertebrate reproduction requires a myriad of precisely orchestrated events-in particular, the maternal production of oocytes, the paternal production of sperm, successful fertilization, and initiation of early embryonic cell divisions. These processes are governed by a host of signaling pathways. Protein kinase and phosphatase signaling pathways involving Mos, CDK1, RSK, and PP2A regulate meiosis during maturation of the oocyte. Steroid signals-specifically testosterone-regulate spermatogenesis, as does signaling by G-protein-coupled hormone receptors. Finally, calcium signaling is essential for both sperm motility and fertilization. Altogether, this signaling symphony ensures the production of viable offspring, offering a chance of genetic immortality.

Indexed as

ReproductionAcrosome ReactionAnimalsCalcium SignalingCell DivisionCell ProliferationFemaleFertilizationHumansMaleMeiosisOocytesSignal TransductionSpermatogenesisSpermatozoaSperm Capacitation

Identifiers

PMID26430215
PMCPMC4588066
OpenAlexW4232035988

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.