Evidence map›Paper›PMID 26430168›Full record

GuidelinePediatrics2015

Early Identification of Autism Spectrum Disorder: Recommendations for Practice and Research.

Lonnie Zwaigenbaum, Margaret L Bauman, Wendy L Stone, Nurit Yirmiya, Annette Estes, Robin L Hansen, James C McPartland, Marvin R Natowicz, Roula Choueiri, Deborah Fein and 12 more

Open access · bronzeAbstract readConsensus StatementPractice Guideline
PubMed Full text at PMC Publisher
In one paragraph

Guideline in Pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 194 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
194citing papers in PubMed, 6 pooled it
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

194 citing papers in PubMed, 6 syntheses or guidelines pooled it, 462 citations in OpenAlex.

  1. Pooled it
  2. Understanding the Effects of Naturalistic Developmental Behavioral Interventions: A Project AIM Meta-analysis.Autism research : official journal of the International Society for Autism Research · 2021
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Guideline
  6. Guideline
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Maternal Extracellular Vesicles During Pregnancy and Autism Risk in Children.medRxiv : the preprint server for health sciences · 2026
    Article
  19. Article
  20. Article

134 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 17 institutions in 3 countries.

Lonnie ZwaigenbaumDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada; lonniez@ualberta.ca.
Margaret L BaumanDepartment of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts;
Wendy L StoneDepartments of Psychology and.
Nurit YirmiyaDepartment of Psychology, Hebrew University of Jerusalem Mount Scopus, Jerusalem, Israel;
Annette EstesSpeech and Hearing Sciences, University of Washington, Seattle, Washington;
Robin L HansenDepartment of Pediatrics, University of California Davis MIND Institute, Sacramento, California;
James C McPartlandYale Child Study Center, New Haven, Connecticut;
Marvin R NatowiczGenomic Medicine Institute, Cleveland Clinic, Cleveland, Ohio;
Roula ChoueiriDivision of Developmental and Behavioral Pediatrics, University of Massachusetts Memorial Children's Medical Center, Worcester, Massachusetts;
Deborah FeinDepartment of Psychology, University of Connecticut, Storrs, Connecticut;
Connie KasariGraduate School of Education & Information Studies, University of California Los Angeles, Los Angeles, California;
Karen PierceDepartment of Neurosciences, University of California San Diego, La Jolla, California;
Timothy BuieHarvard Medical School and Massachusetts General Hospital for Children, Boston, Massachusetts;
Alice CarterDepartment of Psychology, University of Massachusetts, Boston, Massachusetts;
Patricia A DavisIntegrated Center for Child Development, Newton, Massachusetts;
Doreen GranpeeshehCenter for Autism and Related Disorders, Tarzana, California;
Zoe MaillouxDepartment of Occupational Therapy, Thomas Jefferson University, Philadelphia, Pennsylvania;
Craig NewschafferA.J. Drexel Autism Institute, Drexel University, Philadelphia, Pennsylvania;
Diana RobinsA.J. Drexel Autism Institute, Drexel University, Philadelphia, Pennsylvania;
Susanne Smith RoleyUSC Mrs T.H. Chan Division of Occupational Science and Occupational Therapy, Los Angeles, California;
Sheldon WagnerBehavioral Development & Educational Services, New Bedford, Massachusetts; and.
Amy WetherbyDepartment of Clinical Sciences, Florida State University College of Medicine, Tallahassee, Florida.
Drexel University · USBehavioral Health Services · USBoston University · USCenter for Autism and Related Disorders · USChildren's Medical Center · USCleveland Clinic · USFlorida State University · USHebrew University of Jerusalem · ILMassachusetts General Hospital · USThomas Jefferson University · USUniversity of Alberta · CAUniversity of California, Davis · USUniversity of California, Los Angeles · USUniversity of California, San Diego · USUniversity of Connecticut · USUniversity of Massachusetts Boston · USUniversity of Washington · US

Funding

Detection of ASD at the 1st birthday as standard of care: The Get SET Early ModelR01MH104446 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PIERCE, KAREN L · 2014 to 2018
$6.0M
Studying the Biology and Behavior of Autism at 1-Year: The Well-Baby Check-Up AppR01MH080134 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PIERCE, KAREN L · 2008 to 2017
$3.3M
NIMH NIH HHS R01 MH080134NIMH NIH HHS R01 MH104446
6 · The paper itself

Abstract

Early identification of autism spectrum disorder (ASD) is essential to ensure that children can access specialized evidence-based interventions that can help to optimize long-term outcomes. Early identification also helps shorten the stressful "diagnostic odyssey" that many families experience before diagnosis. There have been important advances in research into the early development of ASDs, incorporating prospective designs and new technologies aimed at more precisely delineating the early emergence of ASD. Thus, an updated review of the state of the science of early identification of ASD was needed to inform best practice. These issues were the focus of a multidisciplinary panel of clinical practitioners and researchers who completed a literature review and reached consensus on current evidence addressing the question "What are the earliest signs and symptoms of ASD in children aged ≤24 months that can be used for early identification?" Summary statements address current knowledge on early signs of ASD, potential contributions and limitations of prospective research with high-risk infants, and priorities for promoting the incorporation of this knowledge into clinical practice and future research.

Indexed as

Biomedical ResearchAutism Spectrum DisorderBiomarkersChild, PreschoolEarly DiagnosisHumansInfantRisk AssessmentBiomarkers

Identifiers

PMID26430168
PMCPMC9923897
OpenAlexW2199002398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.