ArticleMolecular biology and evolution2016
Evolution of DNA-Binding Sites of a Floral Master Regulatory Transcription Factor.
Article in Molecular biology and evolution, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- ChIP-Hub provides an integrative platform for exploring plant regulome.Nature communications · 2022Pooled it
- Evolutionary causes and consequences of gene duplication.Nature reviews. Genetics · 2026Review
- Many roads lead to a plant cistrome: mapping and interpreting transcription factor binding in plants.Genome biology · 2026Review
- Factors determining chromosomal localization of transposable elements in plants.Plant biology (Stuttgart, Germany) · 2025Review
- Extensive genome evolution distinguishes maize within a stable tribe of grasses.bioRxiv : the preprint server for biology · 2025Article
- The release of sexual conflict after sex loss is associated with evolutionary changes in gene expression.Proceedings. Biological sciences · 2025Article
- Comprehensive Evolutionary Analysis of theInternational journal of molecular sciences · 2024Article
- Genome-Wide Identification ofPlants (Basel, Switzerland) · 2024Article
- Jasmonic acid negatively regulates branch growth in pear.Frontiers in plant science · 2023Article
- Limited conservation in cross-species comparison of GLK transcription factor binding suggested wide-spread cistrome divergence.Nature communications · 2022Article
- Identification and functional validation of super-enhancers inProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Review
- Insight Into the Multiple Branches Traits of a Mutant inFrontiers in plant science · 2021Article
- Mobility connects: transposable elements wire new transcriptional networks by transferring transcription factor binding motifs.Biochemical Society transactions · 2020Review
- Unwinding BRAHMA Functions in Plants.Genes · 2020Review
- Article
- Enhanced Maps of Transcription Factor Binding Sites Improve Regulatory Networks Learned from Accessible Chromatin Data.Plant physiology · 2019Article
- A conserved leucine zipper-like motif accounts for strong tetramerization capabilities of SEPALLATA-like MADS-domain transcription factors.Journal of experimental botany · 2018Article
- Divergence of regulatory networks governed by the orthologous transcription factors FLC and PEP1 in Brassicaceae species.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- The rewiring of transcription circuits in evolution.Current opinion in genetics & development · 2017Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Flower development is controlled by the action of key regulatory transcription factors of the MADS-domain family. The function of these factors appears to be highly conserved among species based on mutant phenotypes. However, the conservation of their downstream processes is much less well understood, mostly because the evolutionary turnover and variation of their DNA-binding sites (BSs) among plant species have not yet been experimentally determined. Here, we performed comparative ChIP (chromatin immunoprecipitation)-seq experiments of the MADS-domain transcription factor SEPALLATA3 (SEP3) in two closely related Arabidopsis species: Arabidopsis thaliana and A. lyrata which have very similar floral organ morphology. We found that BS conservation is associated with DNA sequence conservation, the presence of the CArG-box BS motif and on the relative position of the BS to its potential target gene. Differences in genome size and structure can explain that SEP3 BSs in A. lyrata can be located more distantly to their potential target genes than their counterparts in A. thaliana. In A. lyrata, we identified transposition as a mechanism to generate novel SEP3 binding locations in the genome. Comparative gene expression analysis shows that the loss/gain of BSs is associated with a change in gene expression. In summary, this study investigates the evolutionary dynamics of DNA BSs of a floral key-regulatory transcription factor and explores factors affecting this phenomenon.
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