Evidence map›Paper›PMID 26429727›Full record

ArticleDrug and alcohol dependence2015

Maternal age and trajectories of cannabis use.

Natacha M De Genna, Marie D Cornelius, Lidush Goldschmidt, Nancy L Day

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

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  10. Observational
  11. Marijuana Use among Young Adults: Who Quits and Why?Health behavior and policy review · 2018
    Article
  12. Maternal Age and Trajectories of Risky Alcohol Use: A Prospective Study.Alcoholism, clinical and experimental research · 2017
    Article
  13. Risk of preterm birth among women using drugs during pregnancy with elevated α-fetoprotein.Journal of perinatology : official journal of the California Perinatal Association · 2017
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Natacha M De GennaDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. Electronic address: degennan@pitt.edu.
Marie D CorneliusDepartments of Psychiatry and Epidemiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. Electronic address: mdc1@pitt.edu.
Lidush GoldschmidtWestern Psychiatric Institute and Clinic (WPIC), University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA. Electronic address: lidush@pitt.edu.
Nancy L DayDepartments of Psychiatry, Epidemiology, Pediatrics, and Occupational Therapy, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. Electronic address: nday@pitt.edu.
University of Pittsburgh · USUniversity of Pittsburgh Medical Center · US

Funding

TEEN TOBACCO USE IN A BIRTH COHORT &PRENATAL EFFECTSR01DA009275 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CORNELIUS, MARIE D. · 1996 to 2009
$3.9M
PRENATAL MARIJUANA EXPOSURE: LONG-TERM OUTCOMESR01DA017786 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DAY, NANCY LEE · 2005 to 2009
$2.4M
Maternal Age, Trajectories of Substance Use, and Health DisparitiesR01DA037209 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DE GENNA, NATACHA · 2014 to 2016
$864k
ALCOHOL USE DURING PREGNANCY: A LONGITUDINAL STUDYR01AA006666 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DAY, NANCY L · 1985 to 2002
$544k
MARIJUANA USE DURING PREGNANCY--A LONGITUDINAL STUDYR01DA003874 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DAY, NANCY L · 1986 to 2000
$441k
EFFECT OF ALCOHOL USE DURING PREGNANCYR01AA006390 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DAY, NANCY L · 1985 to 1986
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NIAAA NIH HHS AA06390NIAAA NIH HHS R01 AA006666NIDA NIH HHS DA037209NIDA NIH HHS DA03874NIDA NIH HHS DA09275NIDA NIH HHS R01 DA009275NIDA NIH HHS R01 DA017786NIDA NIH HHS R01 DA037209
6 · The paper itself

Abstract

backgroundBecoming a mother is a developmental transition that has been linked to desistance from substance use. However, timing of motherhood may be a key determinant of cannabis use in women, based on preliminary evidence from teenage mothers. The goal of this study was to identify trajectories of maternal cannabis use, and to determine if maternal age was associated with different trajectories of use.

methodsThis prospective study examined 456 pregnant women recruited at a prenatal clinic, ranging in age from 13 to 42 years. The women were interviewed about their cannabis use 1 year prior to pregnancy and during each trimester of pregnancy, and at 6, 10, 14, and 16 years post-partum.

resultsA growth mixture model of cannabis use reported at each time point clearly delineated four groups: non/unlikely to use, decreasing likelihood of use, late desistance, and increasing likelihood/chronic use (Lo-Mendell-Rubin adjusted LRT test statistic=35.7, p<.001). The youngest mothers were least likely to be in the "non/unlikely to use" group. Younger maternal age also differentiated between late desistance and increasing likelihood/chronic use, versus decreasing likelihood of use post-partum.

conclusionsThis is the first study to demonstrate that younger mothers are more likely to use cannabis across 17 years, including later desistance post-partum and increasing/chronic use. Other substance use and chronic depressive symptoms were also associated with more frequent use. These findings have implications for both prevention and treatment of cannabis use in mothers.

Indexed as

Maternal AgeAdolescentAdultCohort StudiesDepressionFemaleHostilityHumansMaleMarijuana AbuseMothersPregnancyProspective StudiesSocioeconomic FactorsSubstance-Related DisordersYoung AdultCannabisDesistanceMarijuanaMaternalMotherWomen

Identifiers

PMID26429727
PMCPMC4633363
OpenAlexW2163019892

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.