SynthesisJournal of preventive medicine and public health = Yebang Uihakhoe chi2015
Hormone Replacement Therapy and Risk of Breast Cancer in Korean Women: A Quantitative Systematic Review.
Synthesis in Journal of preventive medicine and public health = Yebang Uihakhoe chi, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Risk factors for breast cancer: an umbrella review of observational cohort studies and causal relationship analysis.Frontiers in oncology · 2025Pooled it
- Helicobacter pylori Infection and Risk of Gastric Cancer in Korea: A Quantitative Systematic Review.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2016Pooled it
- Epstein-Barr Virus and Gastric Cancer Risk: A Meta-analysis With Meta-regression of Case-control Studies.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2016Pooled it
- Association of lifestyle factors with breast cancer incidence: An overview of systematic reviews.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2025Article
- Review
- Attitude, Practices, and Barriers to Menopausal Hormone Therapy Among Physicians in Saudi Arabia.Cureus · 2024Article
- Validating Breast Cancer Risk Prediction Models in the Korean Cancer Prevention Study-II Biobank.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020Article
- Frailty Is Inversely Related to Age at Menopause and Elevated in Women Who Have Had a Hysterectomy: An Analysis of the Canadian Longitudinal Study on Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019Article
- Screening breast magnetic resonance imaging in women with hormone replacement therapy.European journal of medical research · 2018Article
- The Relationship Between Breast Cancer and Risk Factors: A Single-Center Study.European journal of breast health · 2017Article
- Age-associated prognostic and predictive biomarkers in patients with breast cancer.Oncology letters · 2017Article
- Breast Cancer Status in Iran: Statistical Analysis of 3010 Cases between 1998 and 2014.International journal of breast cancer · 2017Article
- Menopause as a potential cause for higher prevalence of low back pain in women than in age-matched men.Journal of orthopaedic translation · 2017Article
- The Risk of Breast Cancer in Women Using Menopausal Hormone Replacement Therapy in Taiwan.International journal of environmental research and public health · 2016Article
- A higher aneurysmal subarachnoid hemorrhage incidence in women prior to menopause: a retrospective analysis of 4,895 cases from eight hospitals in China.Quantitative imaging in medicine and surgery · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe epidemiological characteristics of breast cancer incidence by age group in Korean women are unique. This systematic review aimed to investigate the association between hormone replacement therapy (HRT) and breast cancer risk in Korean women.
methodsWe searched electronic databases such as KoreaMed, KMbase, KISS, and RISS4U as well as PubMed for publications on Korean breast cancer patients. We also conducted manual searching based on references and citations in potential papers. All of the analytically epidemiologic studies that obtained individual data on HRT exposure and breast cancer occurrence in Korean women were selected. We restricted the inclusion of case-control studies to those that included age-matched controls. Estimates of summary odds ratio (SOR) with 95% confidence intervals (CIs) were calculated using random effect models.
resultsOne cohort and five case-control studies were finally selected. Based on the heterogeneity that existed among the six studies (I-squared=70.2%), a random effect model was applied. The summary effect size of HRT history from the six articles indicated no statistical significance in breast cancer risk (SOR, 0.983; 95% CI, 0.620 to 1.556).
conclusionsThese facts support no significant effect of HRT history in the risk of breast cancer in Korean women. It is necessary to conduct a pooled analysis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.