Evidence map›Paper›PMID 26428933›Full record

ReviewJournal of diabetes science and technology2015

Exercise and the Development of the Artificial Pancreas: One of the More Difficult Series of Hurdles.

Michael C Riddell, Dessi P Zaharieva, Loren Yavelberg, Ali Cinar, Veronica K Jamnik

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of diabetes science and technology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03212950 (Day and Night Closed-Loop Glycemic Control With Faster-Acting Insulin Aspart in Young Adults With Type 1 Diabetes Using DreaMed Glucositter - The Fast PHYSI-DREAM Study), which is not on this map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03212950 nacompletednot on this mapstarted 2017, after this paper: background citation

Day and Night Closed-Loop Glycemic Control With Faster-Acting Insulin Aspart in Young Adults With Type 1 Diabetes Using DreaMed Glucositter - The Fast PHYSI-DREAM Study

TypeinterventionalSponsorUniversity of Ljubljana, Faculty of MedicineRan2017 to 2017Enrolled20ConditionsType 1 Diabetes MellitusArmsFast-CL, Regular-CL
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Physical Activity Management for Youth With Type 1 Diabetes: Supporting Active and Inactive Children.Diabetes spectrum : a publication of the American Diabetes Association · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Continuous Glucose Monitoring and Physical Activity.International journal of environmental research and public health · 2022
    Review
  18. Article
  19. Article
  20. Advances in Exercise and Nutrition as Therapy in Diabetes.Diabetes technology & therapeutics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michael C RiddellSchool of Kinesiology and Health Science, Faculty of Health, Physical Activity and Chronic Disease Unit, York University, Toronto, Ontario, Canada mriddell@yorku.ca.
Dessi P ZaharievaSchool of Kinesiology and Health Science, Faculty of Health, Physical Activity and Chronic Disease Unit, York University, Toronto, Ontario, Canada.
Loren YavelbergSchool of Kinesiology and Health Science, Faculty of Health, Physical Activity and Chronic Disease Unit, York University, Toronto, Ontario, Canada.
Ali CinarDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, USA Department of Chemical and Biological Engineering, Illinois Institute of Technology, Chicago, IL, USA.
Veronica K JamnikSchool of Kinesiology and Health Science, Faculty of Health, Physical Activity and Chronic Disease Unit, York University, Toronto, Ontario, Canada.

Funding

Control Systems for Artificial Pancreas Use During and After ExerciseDP3DK101075 · NIDDK · ILLINOIS INSTITUTE OF TECHNOLOGY · PI CINAR, ALI · 2013 to 2013
$2.5M
Fault-tolerant Control Systems for Artificial PancreasDP3DK101077 · NIDDK · ILLINOIS INSTITUTE OF TECHNOLOGY · PI CINAR, ALI · 2013 to 2013
$2.0M
NIDDK NIH HHS 1DP3 DK101077NIDDK NIH HHS DP3 DK101075NIDDK NIH HHS DP3 DK101077
6 · The paper itself

Abstract

Regular physical activity (PA) promotes numerous health benefits for people living with type 1 diabetes (T1D). However, PA also complicates blood glucose control. Factors affecting blood glucose fluctuations during PA include activity type, intensity and duration as well as the amount of insulin and food in the body at the time of the activity. To maintain equilibrium with blood glucose concentrations during PA, the rate of glucose appearance (Ra) to disappearance (Rd) in the bloodstream must be balanced. In nondiabetics, there is a rise in glucagon and a reduction in insulin release at the onset of mild to moderate aerobic PA. During intense aerobic -anaerobic work, insulin release first decreases and then rises rapidly in early recovery to offset a more dramatic increase in counterregulatory hormones and metabolites. An "exercise smart" artificial pancreas (AP) must be capable of sensing glucose and perhaps other physiological responses to various types and intensities of PA. The emergence of this new technology may benefit active persons with T1D who are prone to hypo and hyperglycemia.

Indexed as

ExerciseMotor ActivityPancreas, ArtificialActigraphyAlgorithmsBiomarkersBlood GlucoseDiabetes Mellitus, Type 1Diffusion of InnovationEnergy MetabolismEquipment DesignGlucagonHumansHypoglycemic AgentsInsulinInsulin Infusion SystemsBiomarkersBlood GlucoseGlucagonHypoglycemic AgentsInsulinartificial pancreasexerciseinsulinmetabolism

Identifiers

PMID26428933
PMCPMC4667314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.