Evidence map›Paper›PMID 26428728›Full record

ReviewIrish journal of medical science2016

Adalimumab for refractory pulmonary sarcoidosis.

P A Minnis, M Poland, M P Keane, S C Donnelly

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Irish journal of medical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. State-of-the-Art Treatments for Sarcoidosis.Methodist DeBakey cardiovascular journal · 2022
    Review
  3. Clinical Presentation and Treatment of High-Risk Sarcoidosis.Annals of the American Thoracic Society · 2021
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

P A MinnisSchool of Medicine and Medical Science, College of Life Sciences, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland. paul.minnis@ucd.ie.
M PolandSchool of Medicine and Medical Science, College of Life Sciences, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland.
M P KeaneSchool of Medicine and Medical Science, College of Life Sciences, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland.
S C DonnellyDepartment of Medicine, Trinity Centre for Health Sciences, Tallaght Hospital, Tallaght, Dublin, Ireland.
University College Dublin · IETallaght University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIreland has one of the highest prevalence of sarcoidosis globally. Currently anti-TNF treatment in sarcoidosis is considered on a case-by-case basis particularly in patients who have a sub-optimal response to corticosteroid therapy.

aimsWe report our experience of Adalimumab in a series of refractory pulmonary sarcoidosis and discuss implications for treatment.

conclusionSymptomatic improvement was found in all patients as well as stabilisation or improvement in DLCO sb. Improvements in pulmonary function tests correlated well to radiological stage and length of disease.

Indexed as

AdalimumabAdultBiological ProductsChronic DiseaseFemaleHumansIrelandMaleMiddle AgedRespiratory Function TestsRespiratory System AgentsSarcoidosis, PulmonaryTreatment OutcomeTumor Necrosis Factor-alphaAdalimumabBiological ProductsRespiratory System AgentsTumor Necrosis Factor-alphaAdalimumabBiologicsPulmonaryRefractorySarcoidosis

Identifiers

PMID26428728
OpenAlexW2277108300

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.