ArticleCritical care (London, England)2015
Six-month quality-of-life and functional status of acute respiratory distress syndrome survivors compared to patients at risk: a population-based study.
Article in Critical care (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 47 citations in OpenAlex.
- COVID-19 does not influence functional status after ARDS therapy.Critical care (London, England) · 2023Trial
- A developmentally informed narrative review of Toll-like receptors in adult and pediatric acute respiratory distress syndrome.Annals of translational medicine · 2026Review
- Delirium and Self-Reported Driving Behaviors and Outcomes After Critical Illness.JAMA network open · 2025Article
- Observational
- Long-Term Evolution of Activities of Daily Life (ADLs) in Critically Ill COVID-19 Patients, a Case Series.Healthcare (Basel, Switzerland) · 2023Article
- Functional, imaging, and respiratory evaluation (FIRE) of patients post-hospitalization for COVID-19: protocol for a pilot observational study.Pilot and feasibility studies · 2022Article
- High rates of impaired quality of life and social and economic problems at 6 months after COVID-19-related ARDS.Journal of anesthesia, analgesia and critical care · 2022Article
- One-Year Multidisciplinary Follow-Up of Patients With COVID-19 Requiring Invasive Mechanical Ventilation.Journal of cardiothoracic and vascular anesthesia · 2022Observational
- Methodology of a Large Multicenter Observational Study of Patients with COVID-19 in Spanish Intensive Care Units.Archivos de bronconeumologia · 2022Observational
- Feasibility of Extracting Meaningful Patient Centered Outcomes From the Electronic Health Record Following Critical Illness in the Elderly.Frontiers in medicine · 2022Article
- Long-Term Outcomes in Acute Respiratory Distress Syndrome: Epidemiology, Mechanisms, and Patient Evaluation.Critical care clinics · 2021Review
- Pulmonary Function and Radiologic Features in Survivors of Critical COVID-19: A 3-Month Prospective Cohort.Chest · 2021Observational
- A multi-center phase II randomized clinical trial of losartan on symptomatic outpatients with COVID-19.EClinicalMedicine · 2021Article
- Influence of quality of intensive care on quality of life/return to work in survivors of the acute respiratory distress syndrome: prospective observational patient cohort study (DACAPO).BMC public health · 2020Observational
- Current understanding of the therapeutic benefits of mesenchymal stem cells in acute respiratory distress syndrome.Cell biology and toxicology · 2020Article
- Therapeutic potential of mesenchymal stem/stromal cell-derived secretome and vesicles for lung injury and disease.Expert opinion on biological therapy · 2020Review
- The quality of acute intensive care and the incidence of critical events have an impact on health-related quality of life in survivors of the acute respiratory distress syndrome - a nationwide prospective multicenter observational study.German medical science : GMS e-journal · 2020Observational
- Article
- Therapeutic Effects of Hyaluronic Acid in Bacterial Pneumonia inAmerican journal of respiratory and critical care medicine · 2019Article
- Is a Part Better than the Whole for Cell-based Therapy for Acute Respiratory Distress Syndrome?Anesthesiology · 2019Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
introductionThe long-term attributable burden related to acute respiratory distress syndrome (ARDS) is not fully investigated. The aim of this study is to evaluate the quality of life (QOL) and functional status at 6 months after hospitalization in patients at risk for ARDS who did and did not develop the syndrome.
methodThis is a population-based prospective cohort study of adult patients from Olmsted County, Minnesota, with or at risk for ARDS hospitalized from October 2008 to July 2011. The primary outcomes were changes in QOL and functional status, measured through 12-Item Short Form Survey (SF-12) and Barthel Index (BI) respectively, from baseline to 6 months, compared between survivors who did and did not develop ARDS.
resultsOf 410 patients with or at risk for ARDS, 98 had baseline surveys collected and 67 responded to a 6-month survey (26 ARDS, 41 non-ARDS). Both ARDS and non-ARDS groups had lower physical component of SF-12 at baseline compared to general population (P < 0.001 for both). ARDS patients had poorer baseline functional status compared to non-ARDS (mean BI 80 ± 25 vs. 88 ± 22, P = 0.03). No significant differences were observed for the change between 6 months and baseline BI (delta 2.3 for ARDS vs. 2.0 for non-ARDS, P = 0.5), or mental (delta 2.7 vs. 2.4, P = 0.9) or physical (delta -3 vs. -3.3, P = 0.9) component of SF-12 between survivors with and without ARDS.
conclusionIn this population-based study, decreased QOL and functional status 6 months after hospitalization were largely explained by baseline condition, with similar recovery in survivors who did and did not develop ARDS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.