Evidence map›Paper›PMID 26428396›Full record

SynthesisJournal of cancer survivorship : research and practice2016

The impact of having both cancer and diabetes on patient-reported outcomes: a systematic review and directions for future research.

Pauline A J Vissers, Louise Falzon, Lonneke V van de Poll-Franse, Frans Pouwer, Melissa S Y Thong

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of cancer survivorship : research and practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. The impact of integrative medicine on quality of life in patients with diabetes mellitus and cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  2. Trial
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  8. Elevated glucose levels in melanoma patients - a real-world analysis.Journal of clinical & translational endocrinology · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
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  15. Article
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  18. Eliciting primary care and oncology provider perspectives on diabetes management during active cancer treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pauline A J VissersCoRPS-Center of Research on Psychology in Somatic diseases, Department of Medical and Clinical Psychology, Tilburg University, P.O. Box 90153, 5000 LE, Tilburg, The Netherlands. p.a.j.vissers@tilburguniversity.edu.
Louise FalzonCenter for Behavioral Cardiovascular Health, Columbia University Medical Center, New York, NY, USA.
Lonneke V van de Poll-FranseCoRPS-Center of Research on Psychology in Somatic diseases, Department of Medical and Clinical Psychology, Tilburg University, P.O. Box 90153, 5000 LE, Tilburg, The Netherlands.
Frans PouwerCoRPS-Center of Research on Psychology in Somatic diseases, Department of Medical and Clinical Psychology, Tilburg University, P.O. Box 90153, 5000 LE, Tilburg, The Netherlands.
Melissa S Y ThongCoRPS-Center of Research on Psychology in Somatic diseases, Department of Medical and Clinical Psychology, Tilburg University, P.O. Box 90153, 5000 LE, Tilburg, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis systematic review aims to summarize the current literature regarding potential effects of having both cancer and diabetes on patient-reported outcomes (PROs) and to provide directions for future research.

methodsMEDLINE, The Cochrane Library, CINAHL, and PsycINFO were searched from inception to January 2015. All English peer-reviewed studies that included patients with both cancer and diabetes and assessed PROs were included. All included studies were independently assessed on methodological quality by two investigators.

resultsOf the 3553 identified studies, 10 studies were included and all were considered of high (40%) or adequate (60%) methodological quality. Eight of the 10 studies focused on health-related quality of life (HRQoL), functioning, or symptoms and 2 studies assessed diabetes self-management. Overall, HRQoL and functioning was lower, and symptoms were higher among patients with both cancer and diabetes as compared to having cancer or diabetes alone. Furthermore, one study reported that diabetes self-management was impaired after chemotherapy.

conclusionsHaving both cancer and diabetes resulted in worse PROs compared to having either one of the diseases, however, the considerable heterogeneity of the included studies hampered strong conclusions. Future studies are needed as this research area is largely neglected. As the majority of the included studies focused on HRQoL, future research should address the impact of both diseases on other PROs such as depression, patient empowerment and self-management. IMPLICATIONS FOR CANCER SURVIVOR: Having both cancer and diabetes might result in worse PROs, however, more research is needed as current evidence is scarce.

Indexed as

Patient Outcome AssessmentDiabetes MellitusFemaleHumansMaleNeoplasmsQuality of LifeSurvivorsCancerDiabetesHealth-related quality of lifePatient-reported outcomesSystematic review

Identifiers

PMID26428396
PMCPMC4801990

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.