ArticleBMC pediatrics2015
Low case notification rates of childhood tuberculosis in southern Ethiopia.
Article in BMC pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Mortality in children diagnosed with tuberculosis: a systematic review and meta-analysis.The Lancet. Infectious diseases · 2017Pooled it
- Estimating childhood tuberculosis incidence and under-reporting in Gedeo Zone, Ethiopia: a Bayesian hidden Markov model.IJID regions · 2025Article
- Spatial distribution of paediatric tuberculosis and factors associated with adverse treatment outcomes in Ashanti Region, Ghana: a retrospective analysis.BMC pediatrics · 2025Article
- Test agreement between GeneXpert and urine lipoarabinomannan test for tuberculosis diagnosis among children in Ethiopia.BMC pediatrics · 2025Article
- Epidemiology of childhood tuberculosis and predictors of death among children on tuberculosis treatment in central Ethiopia: an extended Cox model challenged survival analysis.BMC public health · 2023Article
- Implementation of evidence-based multiple focus integrated intensified TB screening to end TB (EXIT-TB) package in East Africa: a qualitative study.BMC infectious diseases · 2023Article
- Southern Ethiopian skilled birth attendant variations and maternal mortality: A multilevel study of a population-based cross-sectional household survey.PLOS global public health · 2023Article
- Characteristics of paediatric patients with tuberculosis and associated determinants of treatment success in Malaysia using the MyTB version 2.1 database over five years.BMC public health · 2020Article
- Tuberculosis surveillance system evaluation: case of Ga West municipality, Ghana, 2011 to 2016.Ghana medical journal · 2020Article
- Declining Trends in Childhood TB Notifications and Profile of Notified Patients in the City of Harare, Zimbabwe, from 2009 to 2018.Journal of tropical medicine · 2020Article
- Prevalence, Associated Risk Factors and Rifampicin Resistance Pattern of Pulmonary Tuberculosis Among Children at Debre Markos Referral Hospital, Northwest, Ethiopia.Infection and drug resistance · 2020Article
- Rifampicin-ResistantInfection and drug resistance · 2020Article
- Epidemiology of childhood tuberculosis and factors associated with unsuccessful treatment outcomes in Tigray, Ethiopia: a ten-year retrospective cross sectional study.BMC public health · 2019Article
- Childhood tuberculosis and treatment outcomes in Accra: a retrospective analysis.BMC infectious diseases · 2019Article
- Comparing tuberculosis in children aged under 5 versus 5 to 14 years old in a rural hospital in southern Ethiopia: an 18-year retrospective cross-sectional study.BMC public health · 2019Article
- [Tuberculosis in children and adolescents in Ecuador: analysis of reporting, disease characteristics and treatment outcomeTuberculose em crianças e adolescentes no Equador: análise da notificação, características da doença e resultados do tratamento].Revista panamericana de salud publica = Pan American journal of public health · 2019Article
- Variability in distribution and use of tuberculosis diagnostic tests in Kenya: a cross-sectional survey.BMC infectious diseases · 2018Article
- Accelerating access to quality TB care for pediatric TB cases through better diagnostic strategy in four major cities of India.PloS one · 2018Observational
- Article
- Conflict and tuberculosis in Sudan: a 10-year review of the National Tuberculosis Programme, 2004-2014.Conflict and health · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChildhood tuberculosis (TB) is a public health concern causing considerable mortality. However, control of childhood TB receives little attention. The control efforts could be inadequate because of challenges associated with difficulties in diagnosing the disease in children. Understanding the burden of the disease among children is important to assess the ongoing transmission of the disease in a community and improving TB control efforts. This study was carried out to assess TB case notification rates (CNRs) and treatment outcomes in children aged less than 15 years over a ten-year period.
methodsData were collected from unit TB registers from all health facilities providing TB treatment in the Sidama Zone in Ethiopia. We analysed the CNRs and treatment outcomes by age category, gender, and place of residence. We used logistic regression analysis to identify factors associated with treatment outcomes and to control for confounding.
resultsA total of 4,656 cases of children less than 15 years of age were notified as diagnosed and treated for TB, constituting 13% of all notified TB cases in the study area. The mean CNRs per 100,000 children less than 15 years were 30 for all new cases of TB, 28 for rural cases, 67 for urban cases, 28 in boys, and 32 in girls. The proportions of treatment success were 82% for new and 77% for retreatment cases for the entire study period and increased to 93% for new cases in 2012 (X(2) trend, P < 0.001). Children less than five years old had a lower treatment success [adjusted odds ratio (AOR) 0.64 (95% CI, 0.52-0.80)] and higher deaths [AOR 2 (95% CI, 1.27-3.12)]. The proportion of children who died during treatment among children in the less than 2-year-old age group was three times higher than children in the 2 year and above age groups [AOR 3.34 (95% CI, 1.92-5.82)].
conclusionThe CNRs of childhood TB were low in Sidama. Children less than 5 years old had a higher proportion of deaths. Efforts need to be made to improve the diagnosis and treatment of TB among children.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.