Evidence map›Paper›PMID 26427758›Full record

ArticleThe EMBO journal2015

cIAP2 supports viability of mice lacking cIAP1 and XIAP.

Kristen N Heard, Mathieu J M Bertrand, Philip A Barker

Open access · bronzeAbstract readLetterComment
In one paragraph

Article in The EMBO journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Cell death in glioblastoma and the central nervous system.Cellular oncology (Dordrecht, Netherlands) · 2025
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Targeting the BIR Domains of Inhibitor of Apoptosis (IAP) Proteins in Cancer Treatment.Computational and structural biotechnology journal · 2019
    Review
  13. Article
  14. Review
  15. Review
  16. Response to Heard et al.The EMBO journal · 2015
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Kristen N HeardDepartment of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC, Canada.
Mathieu J M BertrandVIB Inflammation Research Centre and Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Philip A BarkerDepartment of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC, Canada.
Ghent University · BEMcGill University · CAMontreal Neurological Institute and Hospital · CA

Funding

Canadian Institutes of Health Research 38942
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsFemaleInhibitor of Apoptosis ProteinsMaleReceptor-Interacting Protein Serine-Threonine KinasesReceptors, Tumor Necrosis Factor, Type IInhibitor of Apoptosis ProteinsReceptor-Interacting Protein Serine-Threonine KinasesReceptors, Tumor Necrosis Factor, Type I

Identifiers

PMID26427758
PMCPMC4601659
OpenAlexW1897354190

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.