Evidence map›Paper›PMID 26426680›Full record

ReviewEuropean eating disorders review : the journal of the Eating Disorders Association2015

The Intestinal Microbiome in Bariatric Surgery Patients.

Christine M Peat, Susan C Kleiman, Cynthia M Bulik, Ian M Carroll

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in European eating disorders review : the journal of the Eating Disorders Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06845995 (The Effects of a Synbiotic Supplement on Metabolic & Cognitive Outcomes and Vitamin D Receptor Variants on Bone Health Among Adults), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06845995 nacompletednot on this mapstarted 2023, after this paper: background citation

The Effects of a Synbiotic Supplement on Metabolic & Cognitive Outcomes and Vitamin D Receptor Variants on Bone Health Among Adults

TypeinterventionalSponsorTexas Tech UniversityRan2023 to 2024Enrolled32ConditionsOlder Adults, Bioelectrical Impedance, Appetite Hormones, Metabolic HealthArmsSynbiotic supplement
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Type 2 Diabetes and the Microbiome.Journal of the Endocrine Society · 2022
    Review
  4. The Role of the Gut Microbiome in Pediatric Obesity and Bariatric Surgery.International journal of molecular sciences · 2022
    Review
  5. Reversal and Remission of T2DM - An Update for Practitioners.Vascular health and risk management · 2022
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Observational
  13. Making Sense of … the Microbiome in Psychiatry.The international journal of neuropsychopharmacology · 2019
    Review
  14. Review
  15. Review
  16. Observational
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Christine M PeatDepartment of Psychiatry, University of North Carolina at Chapel Hill, USA.
Susan C KleimanDepartment of Nutrition, University of North Carolina at Chapel Hill, USA.
Cynthia M BulikDepartment of Psychiatry, University of North Carolina at Chapel Hill, USA.
Ian M CarrollDepartment of Medicine, University of North Carolina at Chapel Hill, USA.
University of North Carolina at Chapel Hill · USKarolinska Institutet · SE

Funding

Microbiome-mediated weight, anxiety, and stress dysregulation in anorexia nervosaR01MH105684 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CARROLL, IAN MICHAEL · 2015 to 2019
$3.9M
NIMH NIH HHS R01 MH105684
6 · The paper itself

Abstract

With nearly 39% of the worldwide adult population classified as obese, much of the globe is facing a serious public health challenge. Increasing rates of obesity, coupled with the failure of many behavioural and pharmacological interventions, have contributed to a rise in popularity of bariatric surgery as a treatment for obesity. Surgery-mediated weight loss was initially thought to be a direct result of mechanical alterations causing restriction and calorie malabsorption. However, the mounting evidence suggests that indirect factors influence the accumulation and storage of fat in patients that have undergone this procedure. Given the established impact the intestinal microbiota has on adiposity, it is likely that this complex enteric microbial community contributes to surgery-mediated weight loss and maintenance of weight loss postsurgery. In this review, we discuss the physiological and psychological traits exhibited by bariatric surgery candidates that can be influenced by the intestinal microbiota. Additionally, we detail the studies that investigated the impact of bariatric surgery on the intestinal microbiota in humans and mouse models of this procedure.

Indexed as

Bariatric SurgeryAnimalsGastrointestinal MicrobiomeHumansMiceModels, AnimalObesityTreatment OutcomeWeight Lossbariatric surgerymicrobiome

Identifiers

PMID26426680
PMCPMC5022764
OpenAlexW2109408516

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.