SynthesisMedicine2015
Comparison of Laparoscopic-Assisted Operations and Laparotomy Operations for the Treatment of Hirschsprung Disease: Evidence From a Meta-Analysis.
Synthesis in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Long-term outcomes and quality of life of patients with Hirschsprung disease: a systematic review and meta-analysis.BMC gastroenterology · 2020Pooled it
- Feasibility and efficacy of home rectal irrigation in neonates and early infancy with Hirschsprung disease.Pediatric surgery international · 2019Trial
- Laparoscopic Versus Robotic Yancey-Soave Primary Pull-Through in Rectosigmoid Hirschsprung Disease: A Systematic Review of the Literature.Children (Basel, Switzerland) · 2026Review
- A case series on the outcomes of laparoscopic pull-through surgery combined with Swenson-like technique and intraoperative frozen section biopsy for Hirschsprung's disease in children.Journal of surgical case reports · 2025Article
- Duhamel and transanal endorectal pull-throughs for Hirschsprung disease: a Bayesian network meta-analysis.BMC surgery · 2024Article
- Surgical management of short-segment Hirschsprung disease.World journal of pediatric surgery · 2024Review
- Comparison of the Duhamel Procedure and Transanal Endorectal Pull-through Procedure in the Treatment of Children with Hirschsprung's Disease: A Systematic Review.Journal of clinical medicine · 2023Review
- Post-surgical Outcomes of Different Surgical Techniques in Hirschsprung's Disease: A Literature Review.Cureus · 2023Review
- Robotic-assisted proctosigmoidectomy for Hirschsprung's disease: A multicenter prospective study.World journal of gastroenterology · 2023Article
- Quality of life outcomes in children after surgery for Hirschsprung disease and anorectal malformations: a systematic review and meta-analysis.World journal of pediatric surgery · 2022Review
- Laparoscopic Soave procedure for long-segment Hirschsprung's disease - single-center experience.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2020Article
- Transanal endorectal stepwise gradient muscular cuff cutting pull-through method: Technique refinements and comparison with laparoscopy-assisted procedures.Experimental and therapeutic medicine · 2018Article
- Current status of Hirschsprung's disease: based on a nationwide survey of Japan.Pediatric surgery international · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this meta-analysis is to compare the relative merits among laparoscopic-assisted operations and laparotomy operations for patients with Hirschsprung disease. PubMed, Web of Science, and Wanfang databases were searched for the related articles. We analyzed dichotomous variables by estimating odds ratios (ORs) with their 95% confidence intervals (CIs) and continuous variables using the weighted mean difference (WMD) with the 95% CI. The random-effects model (REM) was used to combine the results. The outcome measures included operating time (OT), estimated blood loss (EBL), length of hospital stay (LOHS), mean first bowel movement (MFBM), and number of complications. Sixteen articles were included in the meta-analysis. These studies involved a total of 774 patients, 396 of whom underwent laparoscopic-assisted operations and 378 of whom underwent laparotomy operations. The EBL (WMD = -1.48, 95% CI = -1.82, -1.13), LOHS (WMD = -0.67, 95% CI = -0.86, -0.49), MFBM (WMD = -0.83, 95% CI = -1.05, -0.61), and number of complications (OR = 0.60, 95% CI = 0.40, 0.89) were significantly lower in laparoscopic-assisted operations than in laparotomy operations. The OT (WMD = 0.12, 95% CI = -0.05, 0.28) showed no significant differences between laparoscopic-assisted operations and laparotomy operations. Compared with laparotomy operations, laparoscopic-assisted operations are generally safer and more reliable for patients with Hirschsprung disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.