Observational studyGynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology2016
Adipokinins in pregnancies at risk of preterm delivery.
Observational study in Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Plasma cytokines during pregnancy provide insight into the risk of diabetes in the gestational diabetes risk group.Journal of diabetes investigation · 2022Article
- Preconception leptin levels and pregnancy outcomes: A prospective cohort study.Obesity science & practice · 2020Article
- Adiponectin and Omentin Levels as Predictive Biomarkers of Preterm Birth in Patients with Gestational Diabetes Mellitus.BioMed research international · 2018Article
- Diagnostic Potential of Evaluation of SDF-1α and sRAGE Levels in Threatened Premature Labor.BioMed research international · 2016Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo compare adipokinins between women experiencing preterm labor (PTL) and prior preterm deliveries (PTD). STUDY
designIn this prospective observational cohort, 110 women with a singleton <35 weeks at increased risk of PTD were studied. Serum leptin, adiponectin, and resistin were obtained at three times (23-34 weeks, 35-36 weeks, at delivery) and analyzed via enzyme-linked immunosorbent assay. The adipokinins were compared across time and between PTL (n = 59) and prior PTD (n = 51) groups using generalized estimated equation models.
resultsThere were no differences in leptin, adiponectin, or resistin levels over the three times between the PTL and PTD groups. There was a trend toward higher leptin levels (p = 0.06 unadjusted analysis, p = 0.09 adjusted analysis) at 23-34 weeks. When stratified by body mass index (BMI), there were differences in leptin (p < 0.001 for BMI < 30; p = 0.77 for BMI ≥ 30) and adiponectin (p = 0.04 for BMI < 30; p = 0.09 for BMI ≥ 30), but not in resistin over the three times between the PTL and prior PTD groups.
conclusionThere were no significant differences in adipokinins in women with PTL and a prior PTD. The trends toward higher leptin levels at 23-34 weeks in women with PTL may represent a compensatory response and require further evaluation in the study of treatments for PTL.
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