Evidence map›Paper›PMID 26426419›Full record

ArticleChemical communications (Cambridge, England)2015

Highly-efficient and versatile fluorous-tagged Cu(I)-catalyzed azide-alkyne cycloaddition ligand for preparing bioconjugates.

Lingyi Sun, Yongkang Gai, Carolyn J Anderson, Dexing Zeng

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lingyi SunDepartment of Radiology, University of Pittsburgh, 100 Technology Drive, Pittsburgh, PA 15219, USA. zengd@upmc.edu.
Yongkang GaiDepartment of Radiology, University of Pittsburgh, 100 Technology Drive, Pittsburgh, PA 15219, USA. zengd@upmc.edu.
Carolyn J AndersonDepartment of Radiology, University of Pittsburgh, 100 Technology Drive, Pittsburgh, PA 15219, USA. zengd@upmc.edu.
Dexing ZengDepartment of Radiology, University of Pittsburgh, 100 Technology Drive, Pittsburgh, PA 15219, USA. zengd@upmc.edu.

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jessie Nedrow · 1988 to 2026
$158.0M
Solid-Phase Platform for the Preparation of Dual-receptor Targeted PET AgentsR21EB017317 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZENG, DEXING · 2013 to 2014
$415k
NCI NIH HHS P30 CA047904NCI NIH HHS P30CA047904NIBIB NIH HHS R21 EB017317NIBIB NIH HHS R21-EB017317
6 · The paper itself

Abstract

A novel ligand (FBTTBE) for Cu(i)-catalyzed azide-alkyne cycloaddition (CuAAC) has been developed, which demonstrates not only superior catalytic efficiency but also the ease of removing toxic copper species. FBTTBE has also been successfully applied in the synthesis of radiometal-labeled peptide and antibody without observable transchelation with the non-radioactive Cu(i) catalyst.

Indexed as

Cycloaddition ReactionAlkynesAnimalsAntibodiesAzidesCatalysisCell Line, TumorCopperCyclizationFluorineGliomaHumansLigandsMiceMice, NudeMolecular StructureAlkynesAntibodiesAzidesCopperFluorineLigandsOrganometallic CompoundsPeptides

Identifiers

PMID26426419
PMCPMC4654650

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.