Evidence map›Paper›PMID 26426342›Full record

ArticlePloS one2015

Predicting Risk of Motor Vehicle Collisions in Patients with Glaucoma: A Longitudinal Study.

Carolina P B Gracitelli, Andrew J Tatham, Erwin R Boer, Ricardo Y Abe, Alberto Diniz-Filho, Peter N Rosen, Felipe A Medeiros

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
8.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  4. Review
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  6. Agreement of driving simulator and on-road driving performance in patients with binocular visual field loss.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018
    Article
  7. Article
  8. Article
  9. Glaucoma: the patient's perspective.The British journal of general practice : the journal of the Royal College of General Practitioners · 2016
    Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Carolina P B GracitelliVisual Performance Laboratory, Department of Ophthalmology, University of California, San Diego, California, United States of America; Department of Ophthalmology, Federal University of São Paulo, São Paulo, São Paulo, Brazil.
Andrew J TathamVisual Performance Laboratory, Department of Ophthalmology, University of California, San Diego, California, United States of America; Princess Alexandra Eye Pavilion and Department of Ophthalmology, University of Edinburgh, Edinburgh, United Kingdom.
Erwin R BoerVisual Performance Laboratory, Department of Ophthalmology, University of California, San Diego, California, United States of America; Entropy Control, Inc., La Jolla, California, United States of America.
Ricardo Y AbeVisual Performance Laboratory, Department of Ophthalmology, University of California, San Diego, California, United States of America; Department of Ophthalmology, University of Campinas, Campinas, São Paulo, Brazil.
Alberto Diniz-FilhoVisual Performance Laboratory, Department of Ophthalmology, University of California, San Diego, California, United States of America; Department of Ophthalmology and Otorhinolaryngology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Peter N RosenVisual Performance Laboratory, Department of Ophthalmology, University of California, San Diego, California, United States of America.
Felipe A MedeirosVisual Performance Laboratory, Department of Ophthalmology, University of California, San Diego, California, United States of America.
University of California, San Diego · USPrincess Alexandra Eye Pavilion · GBPureTemp (United States) · USUniversidade Federal de Minas Gerais · BRUniversidade Federal de São Paulo · BR

Funding

Vision BiostatisticsP30EY022589 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LINDA M ZANGWILL · 2012 to 2026
$10.3M
Diagnostic Innovations in Glaucoma Study (DIGS): Functional ImpairmentR01EY021818 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MEDEIROS, FELIPE · 2011 to 2015
$3.4M
NEI NIH HHS EY021818NEI NIH HHS P30 EY022589NEI NIH HHS P30EY022589NEI NIH HHS R01 EY021818
6 · The paper itself

Abstract

purposeTo evaluate the ability of longitudinal Useful Field of View (UFOV) and simulated driving measurements to predict future occurrence of motor vehicle collision (MVC) in drivers with glaucoma.

designProspective observational cohort study.

participants117 drivers with glaucoma followed for an average of 2.1 ± 0.5 years.

methodsAll subjects had standard automated perimetry (SAP), UFOV, driving simulator, and cognitive assessment obtained at baseline and every 6 months during follow-up. The driving simulator evaluated reaction times to high and low contrast peripheral divided attention stimuli presented while negotiating a winding country road, with central driving task performance assessed as "curve coherence". Drivers with MVC during follow-up were identified from Department of Motor Vehicle records.

main outcome measuresSurvival models were used to evaluate the ability of driving simulator and UFOV to predict MVC over time, adjusting for potential confounding factors.

resultsMean age at baseline was 64.5 ± 12.6 years. 11 of 117 (9.4%) drivers had a MVC during follow-up. In the multivariable models, low contrast reaction time was significantly predictive of MVC, with a hazard ratio (HR) of 2.19 per 1 SD slower reaction time (95% CI, 1.30 to 3.69; P = 0.003). UFOV divided attention was also significantly predictive of MVC with a HR of 1.98 per 1 SD worse (95% CI, 1.10 to 3.57; P = 0.022). Global SAP visual field indices in the better or worse eye were not predictive of MVC. The longitudinal model including driving simulator performance was a better predictor of MVC compared to UFOV (R2 = 0.41 vs R2 = 0.18).

conclusionsLongitudinal divided attention metrics on the UFOV test and during simulated driving were significantly predictive of risk of MVC in glaucoma patients. These findings may help improve the understanding of factors associated with driving impairment related to glaucoma.

Indexed as

GlaucomaAccidents, TrafficAgedAutomobile DrivingFemaleHumansLongitudinal StudiesMaleMiddle AgedRisk AssessmentVisual Fields

Identifiers

PMID26426342
PMCPMC4591330
OpenAlexW2159026571

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.