ReviewInternational journal of molecular sciences2015
An Overview of Predictors for Intrinsically Disordered Proteins over 2010-2014.
Review in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 42 citations in OpenAlex.
- Modern resources for intrinsic disorder predictions: protein language models, deep learning, meta-servers, and databases.Cellular and molecular life sciences : CMLS · 2026Review
- Computational Prediction of Protein Intrinsically Disordered Region Related Interactions and Functions.Genes · 2023Review
- Computational prediction of disordered binding regions.Computational and structural biotechnology journal · 2023Review
- The PentUnFOLD algorithm as a tool to distinguish the dark and the light sides of the structural instability of proteins.Amino acids · 2022Article
- Compositional Bias of Intrinsically Disordered Proteins and Regions and Their Predictions.Biomolecules · 2022Article
- Intrinsically disordered proteins play diverse roles in cell signaling.Cell communication and signaling : CCS · 2022Review
- Deep learning in prediction of intrinsic disorder in proteins.Computational and structural biotechnology journal · 2022Review
- Article
- Tuning intrinsic disorder predictors for virus proteins.Virus evolution · 2021Article
- Comparative Assessment of Intrinsic Disorder Predictions with a Focus on Protein and Nucleic Acid-Binding Proteins.Biomolecules · 2020Review
- The Anti-Inflammatory Protein TNIP1 Is Intrinsically Disordered with Structural Flexibility Contributed by Its AHD1-UBAN Domain.Biomolecules · 2020Article
- Dark Proteome Database: Studies on Disorder.High-throughput · 2020Article
- Genus-specific pattern of intrinsically disordered central regions in the nucleocapsid protein of coronaviruses.Computational and structural biotechnology journal · 2020Article
- Modulation of Disordered Proteins with a Focus on Neurodegenerative Diseases and Other Pathologies.International journal of molecular sciences · 2019Review
- Accurately Predicting Disordered Regions of Proteins Using Rosetta ResidueDisorder Application.The journal of physical chemistry. B · 2018Article
- Bioinformatic Analysis Reveals Conservation of Intrinsic Disorder in the Linker Sequences of Prokaryotic Dual-family Immunophilin Chaperones.Computational and structural biotechnology journal · 2018Article
- Troubleshooting Guide to Expressing Intrinsically Disordered Proteins for Use in NMR Experiments.Frontiers in molecular biosciences · 2018Review
- Comprehensive review of methods for prediction of intrinsic disorder and its molecular functions.Cellular and molecular life sciences : CMLS · 2017Review
- XSuLT: a web server for structural annotation and representation of sequence-structure alignments.Nucleic acids research · 2017Article
- Self-regulation of functional pathways by motifs inside the disordered tails of beta-catenin.BMC genomics · 2016Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The sequence-structure-function paradigm of proteins has been changed by the occurrence of intrinsically disordered proteins (IDPs). Benefiting from the structural disorder, IDPs are of particular importance in biological processes like regulation and signaling. IDPs are associated with human diseases, including cancer, cardiovascular disease, neurodegenerative diseases, amyloidoses, and several other maladies. IDPs attract a high level of interest and a substantial effort has been made to develop experimental and computational methods. So far, more than 70 prediction tools have been developed since 1997, within which 17 predictors were created in the last five years. Here, we presented an overview of IDPs predictors developed during 2010-2014. We analyzed the algorithms used for IDPs prediction by these tools and we also discussed the basic concept of various prediction methods for IDPs. The comparison of prediction performance among these tools is discussed as well.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.