ArticleScience advances2015
Mast cell degranulation by a hemolytic lipid toxin decreases GBS colonization and infection.
Article in Science advances, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 54 citations in OpenAlex.
- Moderating role of blood inflammatory markers in the vaginal microbiota-fibrinogen relationship in URSA-affected women.Scientific reports · 2026Article
- Serotype Distribution, Antibiotic Resistance Characteristics, and Virulence Factor Analysis of Group BInfection and drug resistance · 2026Article
- Group B streptococcal infections in pregnancy and early life.Clinical microbiology reviews · 2025Review
- MASTer cell: chief immune modulator and inductor of antimicrobial immune response.Frontiers in immunology · 2024Review
- Maternal Group B Streptococcus Infection Correlates Inversely With Preeclampsia in Pregnant African American Women.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2024Article
- Siglec-9 is an inhibitory receptor on human mast cells in vitro.The Journal of allergy and clinical immunology · 2023Article
- CD1 and iNKT cells mediate immune responses against the GBS hemolytic lipid toxin induced by a non-toxic analog.PLoS pathogens · 2023Article
- Mast cell-derived factor XIIIA contributes to sexual dimorphic defense against group B streptococcal infections.The Journal of clinical investigation · 2022Article
- Group B Streptococcal Hemolytic Pigment Impairs Platelet Function in a Two-Step Process.Cells · 2022Article
- The role of human mast cells in allergy and asthma.Bioengineered · 2022Review
- Functional Insights into the High-Molecular-Mass Penicillin-Binding Proteins of Streptococcus agalactiae Revealed by Gene Deletion and Transposon Mutagenesis Analysis.Journal of bacteriology · 2021Article
- Hemolytic Membrane Vesicles of Group B Streptococcus Promote Infection.The Journal of infectious diseases · 2021Article
- Physiological Functions of Mcl-1: Insights From Genetic Mouse Models.Frontiers in cell and developmental biology · 2021Review
- Bacterial and Host Determinants of Group B Streptococcal Vaginal Colonization and Ascending Infection in Pregnancy.Frontiers in cellular and infection microbiology · 2021Review
- Genetic Basis Underlying the Hyperhemolytic Phenotype of Streptococcus agalactiae Strain CNCTC10/84.Journal of bacteriology · 2020Article
- Genome-Wide Assessment of Streptococcus agalactiae Genes Required for Survival in Human Whole Blood and Plasma.Infection and immunity · 2020Article
- Roles of a Mast Cell-Specific Receptor MRGPRX2 in Host Defense and Inflammation.Journal of dental research · 2020Article
- Host Cathelicidin Exacerbates Group BmSphere · 2020Article
- Lipid analogs reveal features critical for hemolysis and diminish granadaene mediated Group B Streptococcus infection.Nature communications · 2020Article
- Streptococcal H2O2 inhibits IgE-triggered degranulation of RBL-2H3 mast cell/basophil cell line by inducing cell death.PloS one · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 1 country.
Funding
Abstract
Ascending infection of microbes from the lower genital tract into the amniotic cavity increases the risk of preterm birth, stillbirth, and newborn infections. Host defenses that are critical for preventing ascending microbial infection are not completely understood. Group B
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.