Evidence map›Paper›PMID 26425630›Full record

ArticleJournal of investigative medicine high impact case reports

Histological Regression of Giant Cell Tumor of Bone Following RANK Ligand Inhibition.

Martin F Dietrich, Dominick Cavuoti, Michael Landay, Yull E Arriaga

Abstract read
In one paragraph

Article in Journal of investigative medicine high impact case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Martin F DietrichUniversity of Texas Southwestern Medical Center, Dallas, TX, USA.
Dominick CavuotiUniversity of Texas Southwestern Medical Center, Dallas, TX, USA.
Michael LandayUniversity of Texas Southwestern Medical Center, Dallas, TX, USA.
Yull E ArriagaUniversity of Texas Southwestern Medical Center, Dallas, TX, USA.

Funding

Physician Scientist Oncology Training ProgramT32CA136515 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI SKAPEK, STEPHEN X · 2009 to 2018
$2.2M
NCI NIH HHS T32 CA136515
6 · The paper itself

Abstract

Lung metastases are a rare complication of giant cell tumors of bone. We herein describe an interesting case of histological regression and size reduction of lung metastases originating from a primary giant cell tumor of bone in response to the RANK ligand inhibitor denosumab.

Indexed as

denosumabGiant cell tumorlung metastasesRANK ligand

Identifiers

PMID26425630
PMCPMC4528877

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.