Evidence map›Paper›PMID 26425365›Full record

ArticleAIDS research and treatment2015

The MANGUA Project: A Population-Based HIV Cohort in Guatemala.

Juan Ignacio García, Blanca Samayoa, Meritxell Sabidó, Luis Alberto Prieto, Mikhail Nikiforov, Rodolfo Pinzón, Luis Roberto Santa Marina de León, José Fernando Ortiz, Ernesto Ponce, Carlos Rodolfo Mejía and 3 more

Abstract read
In one paragraph

Article in AIDS research and treatment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Juan Ignacio GarcíaFundació Sida i Societat, Technical Advisor Unit (UAT), Escuintla National Hospital, 5001 Escuintla, Guatemala ; PhD Programme in Methodology of Biomedical Research and Public Health, Department of Paediatrics, Obstetrics, Gynaecology and Preventive Medicine, Universitat Autònoma de Barcelona, Bellaterra, 08193 Catalonia, Spain.
Blanca SamayoaClínica Familiar Luis Ángel García, San Juan de Dios Hospital, Asociación de Salud Integral, 1001 Guatemala City, Guatemala.
Meritxell SabidóFundació Sida i Societat, Technical Advisor Unit (UAT), Escuintla National Hospital, 5001 Escuintla, Guatemala ; TransLab, Department of Medical Sciences, University of Girona, Girona, 17004 Catalonia, Spain.
Luis Alberto PrietoFundació Sida i Societat, Technical Advisor Unit (UAT), Escuintla National Hospital, 5001 Escuintla, Guatemala.
Mikhail NikiforovFundació Sida i Societat, Technical Advisor Unit (UAT), Escuintla National Hospital, 5001 Escuintla, Guatemala.
Rodolfo PinzónInfectious Diseases Clinic, Roosevelt Hospital, 1011 Guatemala City, Guatemala.
Luis Roberto Santa Marina de LeónJuan José Ortega de Coatepeque National Hospital, Coatepeque, 09020 Quetzaltenango, Guatemala.
José Fernando OrtizHospital del Instituto Guatemalteco de Seguridad Social (IGSS), 1009 Guatemala City, Guatemala.
Ernesto PonceNational Programme for Prevention and Control of STI and HIV/AIDS (PNS), 1011 Guatemala City, Guatemala.
Carlos Rodolfo MejíaInfectious Diseases Clinic, Roosevelt Hospital, 1011 Guatemala City, Guatemala.
Eduardo ArathoonClínica Familiar Luis Ángel García, San Juan de Dios Hospital, Asociación de Salud Integral, 1001 Guatemala City, Guatemala.
Jordi CasabonaFundació Sida i Societat, Technical Advisor Unit (UAT), Escuintla National Hospital, 5001 Escuintla, Guatemala ; PhD Programme in Methodology of Biomedical Research and Public Health, Department of Paediatrics, Obstetrics, Gynaecology and Preventive Medicine, Universitat Autònoma de Barcelona, Bellaterra, 08193 Catalonia, Spain ; CIBER Epidemiología y Salud Pública (CIBERESP), 28029 Madrid, Spain ; Center for Epidemiological Studies on HIV/AIDS and STI of Catalonia (CEEISCAT), Institut Català d'Oncologia, Generalitat de Catalunya, Badalona, 08916 Catalonia, Spain.
The Mangua Cohort Study GroupFundació Sida i Societat, Technical Advisor Unit (UAT), Escuintla National Hospital, 5001 Escuintla, Guatemala.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction. The MANGUA cohort is an ongoing multicenter, observational study of people living with HIV/AIDS in Guatemala. The cohort is based on the MANGUA application which is an electronic database to capture essential data from the medical records of HIV patients in care. Methods. The cohort enrolls HIV-positive adults ≥16 years of age. A predefined set of sociodemographic, behavioral, clinical, and laboratory data are registered at entry to the cohort study. Results. As of October 1st, 2012, 21 697 patients had been included in the MANGUA cohort (median age: 33 years, 40.3% female). At enrollment 74.1% had signs of advanced HIV infection and only 56.3% had baseline CD4 cell counts. In the first 12 months after starting antiretroviral treatment 26.9% (n = 3938) of the patients were lost to the program. Conclusions. The implementation of a cohort of HIV-positive patients in care in Guatemala is feasible and has provided national HIV indicators to monitor and evaluate the HIV epidemic. The identified percentages of late presenters and high rates of LTFU will help the Ministry to target their current efforts in improving access to diagnosis and care.

Identifiers

PMID26425365
PMCPMC4575727

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.