Evidence map›Paper›PMID 26425238›Full record

ArticleCanadian Urological Association journal = Journal de l'Association des urologues du Canada

Reproductive outcomes in men with karyotype abnormalities: Case report and review of the literature.

Taylor P Kohn, Raul Clavijo, Ranjith Ramasamy, Tariq Hakky, Aravind Candrashekar, Dolores J Lamb, Larry I Lipshultz

Open access · diamondAbstract read
In one paragraph

Article in Canadian Urological Association journal = Journal de l'Association des urologues du Canada. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Taylor P KohnDepartment of Urology, Baylor College of Medicine, Houston, TX;
Raul ClavijoDepartment of Urology, University of California, Los Angeles, CA.
Ranjith RamasamyDepartment of Urology, Baylor College of Medicine, Houston, TX;
Tariq HakkyDepartment of Urology, Baylor College of Medicine, Houston, TX;
Aravind CandrashekarDepartment of Urology, Baylor College of Medicine, Houston, TX;
Dolores J LambDepartment of Urology, Baylor College of Medicine, Houston, TX;
Larry I LipshultzDepartment of Urology, Baylor College of Medicine, Houston, TX;
Baylor College of Medicine · USUniversity of California, Los Angeles · US

Funding

K-12: Male Reproductive Health Research (MRHR) Career Development Program at BCMK12HD073917 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI LAMB, DOLORES JEAN · 2012 to 2016
$1.7M
NICHD NIH HHS K12 HD073917
6 · The paper itself

Abstract

Reciprocal translocations of autosomal chromosomes are present in about 1/625 men, yet often there are no symptoms except primary infertility. Abnormal segregation during meiosis often produces sperm and subsequent embryos with unbalanced translocations that often ultimately result in spontaneous abortions. We report on a 37-year-old man and his 39-year-old wife who complained of primary infertility. Previous in vitro fertilization (IVF) had resulted in pregnancy, but two spontaneous abortions. Upon chromosomal testing, the man was diagnosed with a reciprocal translocation and his wife was diagnosed with mosaic Turner's syndrome. Through testicular sperm extraction (TESE) and IVF with preimplantation genetic screening (PGS), they succeeded in having two healthy children. Since men with different karyotype abnormalities can have male infertility, we reviewed the literature and summarized the reproductive outcomes for men with both autosome and sex chromosomal karyotype abnormalities.

Identifiers

PMID26425238
PMCPMC4581942
OpenAlexW1839506473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.