Evidence map›Paper›PMID 26425123›Full record

ArticleJournal of cancer epidemiology2015

Occupational Exposure to Diesel Motor Exhaust and Lung Cancer: A Dose-Response Relationship Hidden by Asbestos Exposure Adjustment? The ICARE Study.

Mireille Matrat, Florence Guida, Sylvie Cénée, Joelle Févotte, Matthieu Carton, Diane Cyr, Gwenn Menvielle, Sophie Paget-Bailly, Loredana Radoï, Annie Schmaus and 5 more

Abstract read
In one paragraph

Article in Journal of cancer epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Frequency of Asbestos Exposure and Histological Subtype of Ovarian Carcinoma.International journal of environmental research and public health · 2022
    Article
  3. Scoping Review of 5 Common Occupational Cancers and Their Related Exposures.Medical journal of the Islamic Republic of Iran · 2022
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Mireille MatratINSERM, Centre de Recherche en Epidémiologie et Santé des Populations (CESP), U1018, Equipe Epidémiologie des Cancers, Gènes et Environnement, Bâtiment 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif, France ; Faculté de Médecine, Université Paris Est Créteil, 8 rue du Général Sarrail, 94010 Créteil Cedex, France ; Centre Hospitalier Intercommunal, Service de Pneumologie et Pathologie Professionnelle, 40 Avenue de Verdun, 94010 Créteil, France.
Florence GuidaINSERM, Centre de Recherche en Epidémiologie et Santé des Populations (CESP), U1018, Equipe Epidémiologie des Cancers, Gènes et Environnement, Bâtiment 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif, France.
Sylvie CénéeINSERM, Centre de Recherche en Epidémiologie et Santé des Populations (CESP), U1018, Equipe Epidémiologie des Cancers, Gènes et Environnement, Bâtiment 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif, France.
Joelle FévotteUnité Mixte de Recherche Épidémiologique et de Surveillance Transport Travail Environnement (UMRESTTE), Université Claude Bernard Lyon 1, 69373 Lyon, France.
Matthieu CartonINSERM, Centre de Recherche en Epidémiologie et Santé des Populations (CESP), Unité UMS 011 Equipe Cohortes Épidémiologiques en Population, Bâtiment 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif, France ; Université de Versailles Saint-Quentin, UMS011, Equipe Cohortes Épidémiologiques en Population, Bâtiment 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif, France.
Diane CyrINSERM, Centre de Recherche en Epidémiologie et Santé des Populations (CESP), Unité UMS 011 Equipe Cohortes Épidémiologiques en Population, Bâtiment 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif, France ; Université de Versailles Saint-Quentin, UMS011, Equipe Cohortes Épidémiologiques en Population, Bâtiment 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif, France.
Gwenn MenvielleINSERM, UMR_S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, 56 Boulevard Vincent Auriol, CS81393, 75646 Paris Cedex 13, France ; UPMC Université de la Sorbonne, Université Paris 06, UMRS 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, 56 Boulevard Vincent Auriol, CS81393, 75646 Paris Cedex 13, France.
Sophie Paget-BaillyINSERM, Centre de Recherche en Epidémiologie et Santé des Populations (CESP), Unité UMS 011 Equipe Cohortes Épidémiologiques en Population, Bâtiment 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif, France ; Université de Versailles Saint-Quentin, UMS011, Equipe Cohortes Épidémiologiques en Population, Bâtiment 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif, France.
Loredana RadoïINSERM, Centre de Recherche en Epidémiologie et Santé des Populations (CESP), U1018, Equipe Epidémiologie des Déterminants Sociaux et Professionnels de la Santé, Bâtiment 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif, France ; Faculté de Chirurgie Dentaire, Université Paris Descartes, 1 rue Maurice Arnoux, 92120 Montrouge, France.
Annie SchmausINSERM, Centre de Recherche en Epidémiologie et Santé des Populations (CESP), Unité UMS 011 Equipe Cohortes Épidémiologiques en Population, Bâtiment 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif, France ; Université de Versailles Saint-Quentin, UMS011, Equipe Cohortes Épidémiologiques en Population, Bâtiment 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif, France.
Simona BaraRegistre des Cancers de la Manche, Centre Hospitalier Public du Cotentin, 46 rue Val de Saire, 50102 Cherbourg, France.
Michel VeltenRegistre des Cancers du Bas-Rhin, Département d'Épidémiologie et de Santé Publique, Faculté de Médecine, Université de Strasbourg, 4 rue Kirschleger, 67085 Strasbourg Cedex, France.
Danièle LuceINSERM U1085, IRSET, Campus de Fouillole, BP145, 97154 Pointe à Pitre, Guadeloupe ; Université de Rennes 1, Campus de Fouillole, BP145, 97154 Pointe à Pitre, Guadeloupe.
Isabelle StückerINSERM, Centre de Recherche en Epidémiologie et Santé des Populations (CESP), U1018, Equipe Epidémiologie des Cancers, Gènes et Environnement, Bâtiment 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif, France.
The Icare Study GroupINSERM, Centre de Recherche en Epidémiologie et Santé des Populations (CESP), U1018, Equipe Epidémiologie des Cancers, Gènes et Environnement, Bâtiment 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background. In a French large population-based case-control study we investigated the dose-response relationship between lung cancer and occupational exposure to diesel motor exhaust (DME), taking into account asbestos exposure. Methods. Exposure to DME was assessed by questionnaire. Asbestos was taken into account through a global indicator of exposure to occupational carcinogens or by a specific JEM. Results. We found a crude dose response relationship with most of the indicators of DME exposure, including with the cumulative exposure index. All results were affected by adjustment for asbestos exposure. The dose response relationships between DME and lung cancer were observed among subjects never exposed to asbestos. Conclusions. Exposure to DME and to asbestos is frequently found among the same subjects, which may explain why dose-response relationships in previous studies that adjusted for asbestos exposure were inconsistent.

Identifiers

PMID26425123
PMCPMC4573883

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.