Evidence map›Paper›PMID 26425045›Full record

ArticleJournal of Korean medical science2015

Detection of Rotavirus Genotypes in Korea 5 Years after the Introduction of Rotavirus Vaccines.

Ju-Young Chung, Min-Sung Kim, Tae Woong Jung, Seong Joon Kim, Jin-Han Kang, Seung Beom Han, Sang Yong Kim, Jung Woo Rhim, Hwang-Min Kim, Jae Hong Park and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of Korean medical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 2 countries.

Ju-Young ChungDepartment of Pediatrics, Sanggyepaik Hospital, Inje University College of Medicine, Seoul, Korea.
Min-Sung KimDepartment of Pediatrics, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
Tae Woong JungDepartment of Pediatrics, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
Seong Joon KimDepartment of Pediatrics, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
Jin-Han KangDepartment of Pediatrics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Seung Beom HanDepartment of Pediatrics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Sang Yong KimDepartment of Pediatrics, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.
Jung Woo RhimDepartment of Pediatrics, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Daejeon, Korea.
Hwang-Min KimDepartment of Pediatrics, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea.
Jae Hong ParkDepartment of Pediatrics, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
Dae Sun JoDepartment of Pediatrics, Chonbuk National University Hospital, Chonbuk National University Medical School, Jeonju, Korea.
Sang Hyuk MaDepartment of Pediatrics, Changwon Fatima Hospital, Changwon, Korea.
Hye-Sook JeongDivision of Vaccine Research, Center for Infectious Diseases, National Institute of Health, Korea Centers for Disease Control and Prevention, Cheongwon, Korea.
Doo-Sung CheonDivision of Vaccine Research, Center for Infectious Diseases, National Institute of Health, Korea Centers for Disease Control and Prevention, Cheongwon, Korea.
Jong-Hyun KimDepartment of Pediatrics, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
The Catholic University of Korea St. Vincent's Hospital · KRCenters for Disease Control and Prevention · USThe Catholic University of Korea Seoul St. Mary's Hospital · KRInje University Sanggye Paik Hospital · KRJeonbuk National University Hospital · KRPusan National University Yangsan Hospital · KRThe Catholic University of Korea Daejeon St. Mary's Hospital · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rotavirus (RV) is one of the most important viral etiologic agents of acute gastroenteritis (AGE) in children. Although effective RV vaccines (RVVs) are now used worldwide, novel genotypes and outbreaks resulting from rare genotype combinations have emerged. This study documented RV genotypes in a Korean population of children with AGE 5 yr after the introduction of RVV and assessed potential genotype differences based on vaccination status or vaccine type. Children less than 5-yr-old diagnosed with AGE between October 2012 and September 2013 admitted to 9 medical institutions from 8 provinces in Korea were prospectively enrolled. Stool samples were tested for RV by enzyme immunoassay and genotyped by multiplex reverse-transcription polymerase chain reaction. In 346 patients, 114 (32.9%) were RV-positive. Among them, 87 (76.3%) patients were infected with RV alone. Eighty-six of 114 RV-positive stool samples were successfully genotyped, and their combinations of genotypes were G1P[8] (36, 41.9%), G2P[4] (12, 14.0%), and G3P[8] (6, 7.0%). RV was detected in 27.8% of patients in the vaccinated group and 39.8% in the unvaccinated group (P=0.035). Vaccination history was available for 67 of 86 cases with successfully genotyped RV-positive stool samples; RotaTeq (20, 29.9%), Rotarix (7, 10.4%), unvaccinated (40, 59.7%). The incidence of RV AGE is lower in the RV-vaccinated group compared to the unvaccinated group with no evidence of substitution with unusual genotype combinations.

Indexed as

Mass VaccinationChild, PreschoolFecesGastroenteritisGenotypeHumansInfantRepublic of KoreaReverse Transcriptase Polymerase Chain ReactionRNA, ViralRotavirusRotavirus InfectionsRotavirus VaccinesVaccines, AttenuatedRIX4414 vaccineRNA, ViralRotaTeqRotavirus VaccinesVaccines, AttenuatedChildrenFecesGastroenteritisGenotypeRotavirusVaccine

Identifiers

PMID26425045
PMCPMC4575937
OpenAlexW1880723519

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.