Evidence map›Paper›PMID 26425039›Full record

ArticleJournal of Korean medical science2015

Baseline Characteristics of the Korean Registry of Pulmonary Arterial Hypertension.

Wook-Jin Chung, Yong Bum Park, Chan Hong Jeon, Jo Won Jung, Kwang-Phil Ko, Sung Jae Choi, Hye Sun Seo, Jae Seung Lee, Hae Ok Jung, KORPAH Investigators

Abstract readMulticenter Study
In one paragraph

Article in Journal of Korean medical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wook-Jin ChungDepartment of Cardiovascular Medicine, Gachon Cardiovascular Research Institute, Gachon University Gil Medical Center, Incheon, Korea.
Yong Bum ParkDivision of Pulmonology, Department of Internal Medicine, Hallym University Gangdong Sacred Heart Hospital, Seoul, Korea.
Chan Hong JeonDivision of Rheumatology, Department of Internal Medicine, Soonchunhyang University Hospital, Bucheon, Korea.
Jo Won JungDivision of Pediatric Cardiology, Department of Pediatrics, Yonsei University Severance Hospital, Seoul, Korea.
Kwang-Phil KoDepartment of Preventive Medicine, Gachon University School of Medicine, Incheon, Korea.
Sung Jae ChoiDivision of Rheumatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea.
Hye Sun SeoDivision of Cardiology, Department of Internal Medicine, Soonchunhyang University Hospital, Bucheon, Korea.
Jae Seung LeeDivision of Pulmonology, Department of Internal Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea.
Hae Ok JungDivision of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
KORPAH Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite recent advances in understanding of the pathobiology and targeted treatments of pulmonary arterial hypertension (PAH), epidemiologic data from large populations have been limited to western countries. The aim of the Korean Registry of Pulmonary Arterial Hypertension (KORPAH) was to examine the epidemiology and prognosis of Korean patients with PAH. KORPAH was designed as a nationwide, multicenter, prospective data collection using an internet webserver from September 2008 to December 2011. A total of 625 patients were enrolled. The patients' mean age was 47.6 ± 15.7 yr, and 503 (80.5%) were women. The diagnostic methods included right heart catheterization (n = 249, 39.8%) and Doppler echocardiography (n = 376, 60.2%). The etiologies, in order of frequency, were connective tissue disease (CTD), congenital heart disease, and idiopathic PAH (IPAH) (49.8%, 25.4%, and 23.2%, respectively). Patients with WHO functional class III or IV at diagnosis were 43.4%. In total, 380 (60.8%) patients received a single PAH-specific treatment at the time of enrollment, but only 72 (18.9%) patients received combination therapy. Incident cases during the registry represented 297 patients; therefore, the incidence rate of PAH was 1.9 patients/yr/million people. The 1st-, 2nd-, and 3rd-yr estimated survival rates were 90.8%, 87.8%, and 84.4%, respectively. Although Korean PAH patients exhibited similar age, gender, and survival rate compared with western registries, they showed relatively more CTD-PAH in the etiology and also systemic lupus erythematosus among CTD-PAH. The data suggest that earlier diagnosis and more specialized therapies should be needed to improve the survival of PAH patients.

Indexed as

Databases, FactualRegistriesAdultAgedConnective Tissue DiseasesData CollectionFamilial Primary Pulmonary HypertensionFemaleHeart Defects, CongenitalHumansInternetMaleMiddle AgedPrognosisProspective StudiesPulmonary ArteryHypertension, PulmonaryKoreanPrognosisPulmonary Arterial Hypertension

Identifiers

PMID26425039
PMCPMC4575931

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.