Evidence map›Paper›PMID 26424908›Full record

ArticleCanadian journal of veterinary research = Revue canadienne de recherche veterinaire2015

Antimicrobial effect against different bacterial strains and bacterial adaptation to essential oils used as feed additives.

Antonio Diego Brandão Melo, Amanda Figueiredo Amaral, Gustavo Schaefer, Fernando Bittencourt Luciano, Carla de Andrade, Leandro Batista Costa, Marcos Horácio Rostagno

Open access · greenAbstract read
In one paragraph

Article in Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
  2. Cross-resistance between halquinol and antibiotics of importance in human and animal health.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
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  12. Chemical and Biological Characterization ofPlants (Basel, Switzerland) · 2022
    Article
  13. Article
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  15. Article
  16. Anti-borreliae efficacy of selected organic oils and fatty acids.BMC complementary and alternative medicine · 2019
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Antonio Diego Brandão MeloGraduate Program in Animal Science, School of Agricultural Sciences and Veterinary Medicine, Pontifícia Universidade Católica do Paraná, BR 376 Km 14, São José dos Pinhais, PR 83010-500, Brazil (Melo, Luciano, Andrade, Costa); School of Veterinary Medicine, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Porto Alegre, RS 91540-000, Brazil (Amaral); Seara Alimentos LTDA, Rua Salgado Filho, 69, Centro, São Miguel do Oeste, SC 89900-000, Brazil (Schaefer); Department of Animal Sciences, Purdue University, 915 West State Street, West Lafayette, Indiana 47907, USA (Rostagno).
Amanda Figueiredo AmaralGraduate Program in Animal Science, School of Agricultural Sciences and Veterinary Medicine, Pontifícia Universidade Católica do Paraná, BR 376 Km 14, São José dos Pinhais, PR 83010-500, Brazil (Melo, Luciano, Andrade, Costa); School of Veterinary Medicine, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Porto Alegre, RS 91540-000, Brazil (Amaral); Seara Alimentos LTDA, Rua Salgado Filho, 69, Centro, São Miguel do Oeste, SC 89900-000, Brazil (Schaefer); Department of Animal Sciences, Purdue University, 915 West State Street, West Lafayette, Indiana 47907, USA (Rostagno).
Gustavo SchaeferGraduate Program in Animal Science, School of Agricultural Sciences and Veterinary Medicine, Pontifícia Universidade Católica do Paraná, BR 376 Km 14, São José dos Pinhais, PR 83010-500, Brazil (Melo, Luciano, Andrade, Costa); School of Veterinary Medicine, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Porto Alegre, RS 91540-000, Brazil (Amaral); Seara Alimentos LTDA, Rua Salgado Filho, 69, Centro, São Miguel do Oeste, SC 89900-000, Brazil (Schaefer); Department of Animal Sciences, Purdue University, 915 West State Street, West Lafayette, Indiana 47907, USA (Rostagno).
Fernando Bittencourt LucianoGraduate Program in Animal Science, School of Agricultural Sciences and Veterinary Medicine, Pontifícia Universidade Católica do Paraná, BR 376 Km 14, São José dos Pinhais, PR 83010-500, Brazil (Melo, Luciano, Andrade, Costa); School of Veterinary Medicine, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Porto Alegre, RS 91540-000, Brazil (Amaral); Seara Alimentos LTDA, Rua Salgado Filho, 69, Centro, São Miguel do Oeste, SC 89900-000, Brazil (Schaefer); Department of Animal Sciences, Purdue University, 915 West State Street, West Lafayette, Indiana 47907, USA (Rostagno).
Carla de AndradeGraduate Program in Animal Science, School of Agricultural Sciences and Veterinary Medicine, Pontifícia Universidade Católica do Paraná, BR 376 Km 14, São José dos Pinhais, PR 83010-500, Brazil (Melo, Luciano, Andrade, Costa); School of Veterinary Medicine, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Porto Alegre, RS 91540-000, Brazil (Amaral); Seara Alimentos LTDA, Rua Salgado Filho, 69, Centro, São Miguel do Oeste, SC 89900-000, Brazil (Schaefer); Department of Animal Sciences, Purdue University, 915 West State Street, West Lafayette, Indiana 47907, USA (Rostagno).
Leandro Batista CostaGraduate Program in Animal Science, School of Agricultural Sciences and Veterinary Medicine, Pontifícia Universidade Católica do Paraná, BR 376 Km 14, São José dos Pinhais, PR 83010-500, Brazil (Melo, Luciano, Andrade, Costa); School of Veterinary Medicine, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Porto Alegre, RS 91540-000, Brazil (Amaral); Seara Alimentos LTDA, Rua Salgado Filho, 69, Centro, São Miguel do Oeste, SC 89900-000, Brazil (Schaefer); Department of Animal Sciences, Purdue University, 915 West State Street, West Lafayette, Indiana 47907, USA (Rostagno).
Marcos Horácio RostagnoGraduate Program in Animal Science, School of Agricultural Sciences and Veterinary Medicine, Pontifícia Universidade Católica do Paraná, BR 376 Km 14, São José dos Pinhais, PR 83010-500, Brazil (Melo, Luciano, Andrade, Costa); School of Veterinary Medicine, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Porto Alegre, RS 91540-000, Brazil (Amaral); Seara Alimentos LTDA, Rua Salgado Filho, 69, Centro, São Miguel do Oeste, SC 89900-000, Brazil (Schaefer); Department of Animal Sciences, Purdue University, 915 West State Street, West Lafayette, Indiana 47907, USA (Rostagno).
Pontifícia Universidade Católica do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the antimicrobial activity and determine the minimum bactericidal concentration (MBC) of the essential oils derived from Origanum vulgare (oregano), Melaleuca alternifolia (tea tree), Cinnamomum cassia (cassia), and Thymus vulgaris (white thyme) against Salmonella Typhimurium, Salmonella Enteritidis, Escherichia coli, Staphylococcus aureus and Enterococcus faecalis. The study also investigated the ability of these different bacterial strains to develop adaptation after repetitive exposure to sub-lethal concentrations of these essential oils. The MBC of the essential oils studied was determined by disc diffusion and broth dilution methods. All essential oils showed antimicrobial effect against all bacterial strains. In general, the development of adaptation varied according to the bacterial strain and the essential oil (tea tree > white thyme > oregano). Therefore, it is important to use essential oils at efficient bactericidal doses in animal feed, food, and sanitizers, since bacteria can rapidly develop adaptation when exposed to sub-lethal concentrations of these oils.

Indexed as

Animal FeedAnimalsAnti-Bacterial AgentsBacteriaDrug Resistance, BacterialFood AdditivesOils, VolatilePlant OilsPlantsAnti-Bacterial AgentsFood AdditivesOils, VolatilePlant Oils

Identifiers

PMID26424908
PMCPMC4581672
OpenAlexW2337669303

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.