ReviewCanadian journal of surgery. Journal canadien de chirurgie2015
Significance of CD4+ T-cell count in the management of appendicitis in patients with HIV.
Review in Canadian journal of surgery. Journal canadien de chirurgie, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Acute Appendicitis in Childhood and Adulthood.Deutsches Arzteblatt international · 2020Pooled it
- Entero-Appendiceal Fistula Presenting with Overt Gastrointestinal Bleeding: A Case Report.Surgical case reports · 2026Article
- The Influence of HIV Status on Acute Appendicitis: A Retrospective Study from South Africa.World journal of surgery · 2023Article
- Article
- The clinical characteristics and outcomes of appendicitis in a population with a high HIV-infection prevalence.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2022Article
- Acute appendicitis in people living with HIV: What does the emergency surgeon needs to know?SAGE open medicine · 2021Review
- [Recommendations on treatment of acute appendicitis : Recommendations of an expert group based on the current literature].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2020Review
- HIV Infection: Its Impact on Patients with Appendicitis in Botswana.World journal of surgery · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
summaryIdentification of complicated appendicitis (CA) is critical to the management of appendicitis. However, previous studies have not investigated indicators of CA among patients with HIV or whether it is safe to use conservative treatment for appendicitis in these patients. Among 322 patients with appendicitis, we identified 14 who had HIV. Six of them were operated and 8 were treated with antibiotics; CA was diagnosed in 4. Patients with HIV and CA had a significantly lower CD4+ T-cell count than those with uncomplicated appendicitis. A white blood cell count lower than 7.4 × 10(9)/L was observed exclusively in patients with CA. No patient with HIV whose appendicitis was treated conservatively died or experienced a recurrence. We discuss our findings, which suggest the possibility of conservative treatment of appendicitis in patients with HIV and identification of CA by low CD4+ T-cell count.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.