Evidence map›Paper›PMID 26424684›Full record

ReviewInfection2016

Corynebacterium diphtheriae in a free-roaming red fox: case report and historical review on diphtheria in animals.

Andreas Sing, Regina Konrad, Dominik M Meinel, Norman Mauder, Ingo Schwabe, Reinhard Sting

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Corynebacteria of theMicrobiology spectrum · 2023
    Article
  3. NewPathogens (Basel, Switzerland) · 2022
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Andreas SingNational Consiliary Laboratory for Diphtheria, Bavarian Health and Food Safety Authority, Veterinärstraße 2, 85764, Oberschleißheim, Germany. andreas.sing@lgl.bayern.de.
Regina KonradNational Consiliary Laboratory for Diphtheria, Bavarian Health and Food Safety Authority, Veterinärstraße 2, 85764, Oberschleißheim, Germany.
Dominik M MeinelBavarian Health and Food Safety Authority, Oberschleißheim, Germany.
Norman MauderChemical and Veterinary Investigations Office Stuttgart, Fellbach, Germany.
Ingo SchwabeChemical and Veterinary Investigations Office Stuttgart, Fellbach, Germany.
Reinhard StingChemical and Veterinary Investigations Office Stuttgart, Fellbach, Germany.
Chemisches und Veterinäruntersuchungsamt Stuttgart · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCorynebacterium diphtheriae, the classical causative agent of diphtheria, is considered to be nearly restricted to humans. Here we report the first finding of a non-toxigenic C. diphtheriae biovar belfanti strain in a free-roaming wild animal.

methodsThe strain obtained from the subcutis and mammary gland of a dead red fox (Vulpes vulpes) was characterized by biochemical and molecular methods including MALDI-TOF and Multi Locus Sequence Typing. Since C. diphtheriae infections of animals, usually with close contact to humans, are reported only very rarely, an intense review comprising also scientific literature from the beginning of the 20th century was performed.

resultsBesides the present case, only 11 previously reported C. diphtheriae animal infections could be verified using current scientific criteria.

conclusionsOur report is the first on the isolation of C. diphtheriae from a wildlife animal without any previous human contact. In contrast, the very few unambiguous publications on C. diphtheriae in animals referred to livestock or pet animals with close human contact. C. diphtheriae carriage in animals has to be considered as an exceptionally rare event.

Indexed as

Corynebacterium diphtheriaeDiphtheriaAnimalsFemaleFoxesGermanyMammary Glands, AnimalAnimalsCorynebacterium diphtheriaeDiphtheriaHistorical reviewWildlifeZoonosis

Identifiers

PMID26424684
OpenAlexW2209008363

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.