ArticleBMC infectious diseases2015
High rates of unplanned interruptions from HIV care early after antiretroviral therapy initiation in Nigeria.
Article in BMC infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Retention in Care Among People Living with HIV in Nigeria: A Systematic Review and Meta-analysis.Journal of research in health sciences · 2024Pooled it
- Men missing from the HIV care continuum in sub-Saharan Africa: a meta-analysis and meta-synthesis.Journal of the International AIDS Society · 2022Pooled it
- Being HIV positive and staying on antiretroviral therapy in Africa: A qualitative systematic review and theoretical model.PloS one · 2019Pooled it
- A Mobile Game Intervention for Young Persons Living With HIV and Depression in Nigeria: Protocol for a Pilot Randomized Controlled Trial.JMIR research protocols · 2025Article
- Characterizing treatment interruptions in the OPERA cohort and virologic outcomes after resumption with bictegravir/emtricitabine/tenofovir alafenamide.AIDS research and therapy · 2025Article
- Factors associated with the interruption of antiretroviral therapy among people living with HIV/AIDS in Brazilian municipalities between 2019 and 2022.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2025Article
- Patient-reported Reasons for Stopping Care or Switching Clinics in Zambia: A Multisite, Regionally Representative Estimate Using a Multistage Sampling-based Approach in Zambia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Antiretroviral treatment interruption among people living with HIV during COVID-19 outbreak in China: a nationwide cross-sectional study.Journal of the International AIDS Society · 2020Article
- The impact of user fees on uptake of HIV services and adherence to HIV treatment: Findings from a large HIV program in Nigeria.PloS one · 2020Article
- High Medication Possession Ratios Associated With Greater Risk of Virologic Failure Among Youth Compared With Adults in a Nigerian Cohort.Journal of acquired immune deficiency syndromes (1999) · 2018Article
- The patient-centered medical home: a reality for HIV care in Nigeria.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2017Article
- Article
- Age Matters: Increased Risk of Inconsistent HIV Care and Viremia Among Adolescents and Young Adults on Antiretroviral Therapy in Nigeria.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2016Article
- Risk factors for unstructured treatment interruptions and association with survival in low to middle income countries.AIDS research and therapy · 2016Article
- High Rates of Unplanned Care Interruption: Implications for Program Response.Health care. Current reviews · 2015Article
- Impact of Unplanned Care Interruption on CD4 Response Early After ART Initiation in a Nigerian Cohort.Journal of the International Association of Providers of AIDS CareArticle
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9 authors.
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Abstract
backgroundUnplanned care interruption (UCI) challenges effective HIV treatment. We determined the frequency and risk factors for UCI in Nigeria.
methodsWe conducted a retrospective-cohort study of adults initiating antiretroviral therapy (ART) between January 2009 and December 2011. At censor, patients were defined as in care, UCI, or inactive. Associations between baseline factors and UCI rates were quantified using Poisson regression.
resultsAmong 2,496 patients, 44 % remained in care, 35 % had ≥1 UCI, and 21 % became inactive. UCI rates were higher in the first year on ART (39/100PY), than the second (19/100PY), third (16/100PY), and fourth (14/100PY) years (p < 0.001). In multivariate analysis, baseline CD4 > 350/uL (IRR 3.21, p < 0.0001), being a student (IRR 1.95, p < 0.0001), and less education (IRR 1.58, p = 0.001) increased risk for UCI. Fifty-five percent of patients with UCI and viral load data had HIV viral load > 1,000 copies/ml upon return to care. DISCUSSION: UCI were observed in over one-third of patients treated, and were most common in the first year on ART. High baseline CD4 count at ART initiation was the greatest predictor of subsequent UCI.
conclusionsInterventions focused on the first year on ART are needed to improve continuity of HIV care.
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