Evidence map›Paper›PMID 26423892›Full record

ArticleCritical care (London, England)2015

Effect of end-stage renal disease on long-term survival after a first-ever mechanical ventilation: a population-based study.

Chin-Ming Chen, Chih-Cheng Lai, Kuo-Chen Cheng, Shih-Feng Weng, Wei-Lun Liu, Hsiu-Nien Shen

Abstract read
In one paragraph

Article in Critical care (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chin-Ming ChenDepartment of Recreation and Health-Care Management, Chia Nan University of Pharmacy and Science, No.60, Sec. 1, Erren Road., Rende District, Tainan, 71710, Taiwan. chencm3383@yahoo.com.tw.
Chih-Cheng LaiDepartment of Intensive Care Medicine, Chi Mei Medical Center, Liouying District, 201, Taikang, Taikang Village, Liouying District, Tainan, 736, Taiwan. dtmed141@gmail.com.
Kuo-Chen ChengDepartment of Internal Medicine, Chi Mei Medical Center, 901 Chung Hwa Road, Yungkang District, Tainan, 710, Taiwan. kuochen@ms1.hinet.net.
Shih-Feng WengDepartment of Hospital and Health Care Administration, Chia Nan University of Pharmacy and Science, Tainan, Taiwan. also99@gmail.com.
Wei-Lun LiuDepartment of Intensive Care Medicine, Chi Mei Medical Center, 901 Chung Hwa Road, Yungkang District, Tainan, 710, Taiwan. medrpeterliu@gmail.com.
Hsiu-Nien ShenDepartment of Intensive Care Medicine, Chi Mei Medical Center, 901 Chung Hwa Road, Yungkang District, Tainan, 710, Taiwan. hsiunian@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with end-stage renal disease (ESRD(Pos)) usually have multiple comorbidities and are predisposed to acute organ failure and in-hospital mortality. We assessed the effect of ESRD on the poorly understood long-term mortality risk after a first-ever mechanical ventilation (1-MV) for acute respiratory failure.

methodsThe data source was Taiwan's National Health Insurance (NHI) Research Database. All patients given a 1-MV between 1999 and 2008 from one million randomly selected NHI beneficiaries were identified (n = 38,659). Patients with or without ESRD (ESRD(Neg)) after a 1-MV between 1999 and 2008 were retrospectively compared and followed from the index admission date to death or the end of 2011. ESRD(Pos) patients (n = 1185; mean age: 65.9 years; men: 51.5 %) were individually matched to ESRD(Neg) patients (ratio: 1:8) using a propensity score method. The primary outcome was death after a 1-MV. The effect of ESRD on the risk of death after MV was assessed. A Cox proportional hazard regression model was used to assess how ESRD affected the mortality risk after a 1-MV.

resultsThe baseline characteristics of the two cohorts were balanced, but the incidence of mortality was higher in ESRD(Pos) patients than in ESRD(Neg) patients (342.30 versus 179.67 per 1000 person-years; P <0.001; covariate-adjusted hazard ratio: 1.43; 95 % confidence interval: 1.31-1.51). For patients who survived until discharge, ESRD was not associated with long-term (>4 years) mortality.

conclusionsESRD increased the mortality risk after a 1-MV, but long-term survival seemed similar.

Indexed as

AdultAgedAged, 80 and overCohort StudiesComorbidityFemaleHospital MortalityHumansKidney Failure, ChronicMaleMiddle AgedRenal DialysisRespiration, ArtificialRetrospective StudiesRisk FactorsSurvivors

Identifiers

PMID26423892
PMCPMC4589902

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.