ArticlePublic health action2014
Retention and HIV seroconversion among drug users on methadone maintenance treatment in Yunnan, China.
Article in Public health action, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Risk factors for poor treatment outcomes among opioid-dependent clients taking methadone in Mombasa, Kenya.Advances in drug and alcohol research · 2024Article
- Influence of social network on drug use among clients of methadone maintenance treatment centers in Kunming, China.PloS one · 2018Article
- HIV seroconversion and risk factors among drug users receiving methadone maintenance treatment in China: A qualitative study.Drug and alcohol dependence · 2016Article
- Does research through Structured Operational Research and Training (SORT IT) courses impact policy and practice?Public health action · 2016Article
- Article
- Challenges in expanding access to antiretroviral therapy for key affected populations.Public health action · 2014Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
settingThirteen methadone maintenance treatment (MMT) clinics across Yunnan, the province with the highest human immunodeficiency virus (HIV) burden in China.
objectivesTo determine, among HIV-negative participants on MMT, the proportion lost to follow-up (defined as those who missed the 6-monthly follow-up examination), factors associated with loss to follow-up (LFU), HIV seroconversion rate and factors associated with seroconversion.
designProspective cohort study from October 2008 to April 2011. All participants were administered a pre-tested structured questionnaire to capture associated factors and offered HIV testing every 6 months. χ(2) test and log-binomial regression were used for data analysis.
resultsOf 1146 participants, 541 (47%) were lost to follow-up in 2.5 years. Factors associated with higher LFU proportion include <6 months of previous MMT, inconvenient location of the MMT clinic and average methadone dose ⩽60 mg/day, with adjusted relative risks (RRs) of respectively 1.4 (95%CI 1.2-1.5), 1.2 (95%CI 1.0-1.4) and 1.1 (95%CI 1.0-1.3). The overall HIV seroconversion rate was 6.6 (95%CI 3.7-11.0) per 1000 person-years. Not living with a partner contributed to higher HIV rates, with an adjusted RR of 3.6 (95%CI 1.0-12.8).
conclusionThe retention rate of MMT participants in Yunnan was not satisfactory. Decentralising service delivery in the community and making directly observed treatment more convenient has the potential to improve retention.
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