ArticleGeneral hospital psychiatry
Adherence to common cardiovascular medications in patients with schizophrenia vs. patients without psychiatric illness.
Article in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Prevalence and predictors of medication non-adherence among people living with multimorbidity: a systematic review and meta-analysis.BMJ open · 2021Pooled it
- Mental disorders, mortality following myocardial infarction, and the impact of the COVID-19 pandemic in England: a cohort study.European heart journal. Quality of care & clinical outcomes · 2026Article
- Secretagogue laxatives as a potential strategy to overcome adherence barriers to over-the-counter treatment for clozapine-induced constipation.The mental health clinician · 2026Article
- Psychiatric Medication Adherence in the United States Before and During the COVID-19 Pandemic.Pharmacoepidemiology and drug safety · 2025Article
- Machine Learning and Interpretability Study for Predicting 30-Day Unplanned Readmission Risk of Schizophrenia: A Retrospective Study.Neuropsychiatric disease and treatment · 2025Article
- Adherence of patients with schizophrenia to hypothyroidism treatment.Global mental health (Cambridge, England) · 2023Article
- Impaired long-term outcomes of patients with schizophrenia spectrum disorder after coronary artery bypass surgery: nationwide case-control study.BJPsych open · 2022Article
- Cardiovascular disease in patients with severe mental illness.Nature reviews. Cardiology · 2021Review
- Risk Factor for Retreatment Episode on Admission Among TB Patients With Schizophrenia.Frontiers in psychiatry · 2021Article
- Positive Airway Pressure Adherence in Patients with Obstructive Sleep Apnea with Schizophrenia.Lung · 2020Article
- Chronic pain diagnoses and opioid dispensings among insured individuals with serious mental illness.BMC psychiatry · 2020Article
- Physical Comorbidities are Independently Associated with Higher Rates of Psychiatric Readmission in a Chinese Han Population.Neuropsychiatric disease and treatment · 2020Article
- Association of Secondary Preventive Cardiovascular Treatment After Myocardial Infarction With Mortality Among Patients With Schizophrenia.JAMA psychiatry · 2018Article
- Preventive Service Use Among People With and Without Serious Mental Illnesses.American journal of preventive medicine · 2018Article
- Statin prescribing for people with severe mental illnesses: a staggered cohort study of 'real-world' impacts.BMJ open · 2017Article
- Cardiovascular disease treatment among patients with severe mental illness: a data linkage study between primary and secondary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2016Article
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 1 country.
Funding
Abstract
objectiveThe purpose of the study was to examine whether individuals with diagnoses of schizophrenia were differentially adherent to their statin or angiotensin-converting enzyme inhibitor/angiotensin receptor blocker (ACEI/ARB) medications compared to individuals without psychiatric illness.
methodUsing electronic medical record data across 13 Mental Health Research Network sites, individuals with diagnoses of schizophrenia or schizoaffective disorder receiving two or more medication dispensings of a statin or an ACEI/ARB in 2011 (N=710) were identified and matched on age, sex and Medicare status to controls with no documented mental illness and two or more medication dispensings of a statin in 2011 (N=710). Medication adherence, and sociodemographic and clinical characteristics of the study population were assessed.
resultsMultivariable models indicated that having a schizophrenia diagnosis was associated with increased odds of statin medication adherence; the odds ratio suggested a small effect. After adjustment for medication regimen, schizophrenia no longer showed an association with statin adherence. Having a schizophrenia diagnosis was not associated with ACEI/ARB medication adherence.
conclusionsCompared to patients without any psychiatric illness, individuals with schizophrenia were marginally more likely to be adherent to their statin medications. Given that patterns of adherence to cardioprotective medications may be different from patterns of adherence to antipsychotic medications, improving adherence to the former may require unique intervention strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.