ArticleJournal of the Royal Society, Interface2015
In vitro degradability, bioactivity and primary cell responses to bone cements containing mesoporous magnesium-calcium silicate and calcium sulfate for bone regeneration.
Article in Journal of the Royal Society, Interface, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 31 citations in OpenAlex.
- Limitations and modifications in the clinical application of calcium sulfate.Frontiers in surgery · 2024Review
- An injectable pH neutral bioactive glass-based bone cement with suitable bone regeneration ability.Journal of orthopaedic translation · 2022Article
- Adsorption of Recombinant Human β-Defensin 2 and Two Mutants on Mesoporous Silica Nanoparticles and Its Effect againstNanomaterials (Basel, Switzerland) · 2021Article
- Pearl Powder-An Emerging Material for Biomedical Applications: A Review.Materials (Basel, Switzerland) · 2021Review
- A Facile Synthesis Process and Evaluations of α-Calcium Sulfate Hemihydrate for Bone Substitute.Materials (Basel, Switzerland) · 2020Article
- Article
- Rheological and Mechanical Properties of Thermoresponsive Methylcellulose/Calcium Phosphate-Based Injectable Bone Substitutes.Materials (Basel, Switzerland) · 2018Article
- Influences of mesoporous magnesium calcium silicate on mineralization, degradability, cell responses, curcumin release from macro-mesoporous scaffolds of gliadin based biocomposites.Scientific reports · 2018Article
- 3D-printed scaffolds of mesoporous bioglass/gliadin/polycaprolactone ternary composite for enhancement of compressive strength, degradability, cell responses and new bone tissue ingrowth.International journal of nanomedicine · 2018Article
- Novel bioactive glass based injectable bone cement with improved osteoinductivity and its in vivo evaluation.Scientific reports · 2017Article
- Effect of Aminated Mesoporous Bioactive Glass Nanoparticles on the Differentiation of Dental Pulp Stem Cells.PloS one · 2016Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mesoporous calcium sulfate-based bone cements (m-CSBC) were prepared by introducing mesoporous magnesium-calcium silicate (m-MCS) with specific surface area (410.9 m² g(-1)) and pore volume (0.8 cm³ g(-1)) into calcium sulfate hemihydrate (CSH). The setting time of the m-CSBC was longer with the increase of m-MCS content while compressive strength decreased. The degradation ratio of m-CSBC increased from 48.6 w% to 63.5 w% with an increase of m-MCS content after soaking in Tris-HCl solution for 84 days. Moreover, the m-CSBC containing m-MCS showed the ability to neutralize the acidic degradation products of calcium sulfate and prevent the pH from dropping. The apatite could be induced on m-CSBC surfaces after soaking in SBF for 7 days, indicating good bioactivity. The effects of the m-CSBC on vitamin D3 sustained release behaviours were investigated. It was found that the cumulative release ratio of vitamin D3 from the m-CSBC significantly increased with the increase of m-MCS content after soaking in PBS (pH = 7.4) for 25 days. The m-CSBC markedly improved the cell-positive responses, including the attachment, proliferation and differentiation of MC3T3-E1 cells, suggesting good cytocompatibility. Briefly, m-CSBC with good bioactivity, degradability and cytocompatibility might be an excellent biocement for bone regeneration.
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