ArticleNeurology2015
Age-specific association of migraine with cryptogenic TIA and stroke: Population-based study.
Article in Neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 66 citations in OpenAlex.
- Zhengtian Capsule versus flunarizine in patients with migraine: a multi-center, double-blind, double-dummy, randomized controlled, non-inferior clinical trial.BMC complementary and alternative medicine · 2016Trial
- Migraine and Cardiovascular Risk: A Scoping Review of Vascular Outcomes, Risk Assessment, and Endothelial Dysfunction.Life (Basel, Switzerland) · 2026Review
- Menopause, Perimenopause, and Migraine: Understanding the Intersections and Implications for Treatment.Neurology and therapy · 2025Review
- Migraine and stroke: correlation, coexistence, dependence - a modern perspective.The journal of headache and pain · 2025Review
- Stroke etiology and white matter burden in women with and without migraine.The journal of headache and pain · 2025Article
- Causality between migraine and cardiovascular disease: a bidirectional Mendelian randomization study.The journal of headache and pain · 2024Article
- Association of Traditional and Nontraditional Risk Factors in the Development of Strokes Among Young Adults by Sex and Age Group: A Retrospective Case-Control Study.Circulation. Cardiovascular quality and outcomes · 2024Article
- Reviewing migraine-associated pathophysiology and its impact on elevated stroke risk.Frontiers in neurology · 2024Review
- Sex Differences in Patients With Cryptogenic Cerebrovascular Events Undergoing Transcatheter Closure of Patent Foramen Ovale.Journal of the American Heart Association · 2023Article
- Bibliometric Analysis of Research on Migraine-Stroke Association from 2013 to 2023.Journal of pain research · 2023Article
- Cerebral Hemodynamics, Right-to-Left Shunt and White Matter Hyperintensities in Patients with Migraine with Aura, Young Stroke Patients and Controls.International journal of environmental research and public health · 2022Article
- Sex and Gender Considerations in Episodic Migraine.Current pain and headache reports · 2022Review
- Glucose-Related Traits and Risk of Migraine-A Potential Mechanism and Treatment Consideration.Genes · 2022Review
- Shorter visual aura characterizes young and middle-aged stroke patients with migraine with aura.Journal of neurology · 2022Article
- Cryptogenic Ischemic Stroke in Migraine: Role of Patent Foramen Ovale.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- The Association between Migraine and Abdominal Aortic Aneurysms: A Nationwide Population-Based Cohort Study.International journal of environmental research and public health · 2021Article
- Sex Differences in Risk Profile, Stroke Cause and Outcome in Ischemic Stroke Patients With and Without Migraine.Frontiers in neuroscience · 2021Article
- Pathophysiological Bases of Comorbidity in Migraine.Frontiers in human neuroscience · 2021Review
- The bucket test differentiates patients with MRI confirmed brainstem/cerebellar lesions from patients having migraine and dizziness alone.BMC neurology · 2019Article
- Prevalence and clinical profile of migraine with aura in a cohort of young patients with stroke: a preliminary retrospective analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019Article
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5 authors at 1 institution in 1 country.
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Abstract
objectiveTo determine whether there is an association between previous migraine and cryptogenic TIA or ischemic stroke at older ages.
methodsWe determined the age-specific associations of history of migraine and Trial of Org 10172 in Acute Stroke Treatment (TOAST) subtype of TIA and ischemic stroke in a population-based cohort study (Oxford Vascular Study; 2002-2012).
resultsAmong 1,810 eligible patients with TIA or ischemic stroke, 668 (36.9%) had cryptogenic events, of whom 187 (28.0%) had previous migraine. Migraine was more commonly associated with cryptogenic events than with those of known etiology (odds ratio [OR] 1.73, 95% confidence interval [CI] 1.38-2.16, p < 0.0001; cardioembolic 2.00, 1.50-2.66, p < 0.0001; large artery 1.75, 1.20-2.53, p = 0.003; small vessel 1.32, 0.95-1.83, p = 0.096). The association of migraine with cryptogenic events was independent of age, sex, and all measured vascular risk factors (RFs) (adjusted OR 1.68, 1.33-2.13, p < 0.0001) and was strongest at older ages (<55 years, OR 1.11, 0.55-2.23; 55-64 years, 1.48, 0.83-2.63; ≥65 years, 1.81, 1.39-2.36) and in patients without vascular RFs (0 RFs OR 2.62, 1.33-5.15; 1 RF 2.01, 1.35-3.01; 2 RFs 1.80, 1.21-2.68; 3 RFs 1.21, 0.71-2.07; 4 RFs 0.92, 0.28-2.99). Results were consistent for migraine with or without aura and for analyses excluding TIA or stratified by sex or vascular territory of event.
conclusionsIn this population-based study of stroke etiology stratified by age, migraine was most strongly associated with cryptogenic TIA and ischemic stroke, particularly at older ages, suggesting a causal role or a shared etiology.
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