Evidence map›Paper›PMID 26423392›Full record

ReviewEcotoxicology (London, England)2015

Toxicological challenges to microbial bioethanol production and strategies for improved tolerance.

Hannah Akinosho, Thomas Rydzak, Abhijeet Borole, Arthur Ragauskas, Dan Close

Abstract readReview
PubMed Publisher
In one paragraph

Review in Ecotoxicology (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Enhanced Biosynthesis ofApplied biochemistry and biotechnology · 2022
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hannah AkinoshoRenewable BioProducts Institute, Georgia Institute of Technology, Atlanta, GA, USA.
Thomas RydzakBioEnergy Science Center, Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN, 37831, USA.
Abhijeet BoroleBiosciences Division, Oak Ridge National Laboratory, P.O. Box 2008, MS6342, Oak Ridge, TN, 37831-6342, USA.
Arthur RagauskasRenewable BioProducts Institute, Georgia Institute of Technology, Atlanta, GA, USA.
Dan CloseBiosciences Division, Oak Ridge National Laboratory, P.O. Box 2008, MS6342, Oak Ridge, TN, 37831-6342, USA. closedm@ornl.gov.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioethanol production output has increased steadily over the last two decades and is now beginning to become competitive with traditional liquid transportation fuels due to advances in engineering, the identification of new production host organisms, and the development of novel biodesign strategies. A significant portion of these efforts has been dedicated to mitigating the toxicological challenges encountered across the bioethanol production process. From the release of potentially cytotoxic or inhibitory compounds from input feedstocks, through the metabolic co-synthesis of ethanol and potentially detrimental byproducts, and to the potential cytotoxicity of ethanol itself, each stage of bioethanol production requires the application of genetic or engineering controls that ensure the host organisms remain healthy and productive to meet the necessary economies required for large scale production. In addition, as production levels continue to increase, there is an escalating focus on the detoxification of the resulting waste streams to minimize their environmental impact. This review will present the major toxicological challenges encountered throughout each stage of the bioethanol production process and the commonly employed strategies for reducing or eliminating potential toxic effects.

Indexed as

BacteriaBiofuelsEthanolIndustrial WasteSaccharomyces cerevisiaeBiofuelsEthanolIndustrial WasteBioethanolBiofuelsFermentationProcess engineeringToxicology

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.